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A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006)

StatusCompleted
PhasePhase 1
Started
View on ClinicalTrials.gov ↗

Record History

  1. Notable Lead sponsor: Merck Sharp & Dohme LLC to Merck Sharp & Dohme LLC Trial completed · Enrollment target: estimated 52 to confirmed 53 · Primary and study completion dates changed from estimate of Sep 3, 2026 to Sep 2, 2026 · 1 more Show 4 more changesShow less
    • Trial completed
    • Enrollment target: estimated 52 to confirmed 53
    • Primary and study completion dates changed from estimate of Sep 3, 2026 to Sep 2, 2026
    • Eligibility criteria expanded, about 8 words
  2. Minor Enrollment closed, study ongoing Site details revised at 5 of 5 sitesv6 Show 1 more changeShow less
    • Site details revised at 5 of 5 sites
  3. Minor Primary and study completion dates: Aug 28, 2026 to Sep 3, 2026v5
  4. Minor Study sites: 4 to 5v4
  5. Minor Site details revised at 2 of 4 sitesv3
  6. Notable Trial status: Not Yet Recruiting to Recruiting Study sites: 0 to 4 · Start date changed from estimate of Dec 18, 2025 to Dec 22, 2025v2 Show 2 more changesShow less
    • Study sites: 0 to 4
    • Start date changed from estimate of Dec 18, 2025 to Dec 22, 2025
  7. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
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The purpose of this study is to learn about the safety and if people tolerate a study medicine called MK-1403. The study will also measure what happens to MK-1403 in the body of a person with type 2 diabetes (T2D) over time (pharmacokinetic or PK study), and how it affects the amount of high-sensitivity C-reactive protein (hsCRP) in a person's blood.
Trial Details
NCT Number NCT07242469
Lead Sponsor Merck Sharp & Dohme LLC
Conditions Diabetes Mellitus, Type 2
Enrollment 53 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov