Radiation-induced Toxicity of the Heart

Late side effects in radio(chemo)therapy \[R(CH)T\] pose a critical limitation to patients' overall survival and quality of life. Even though toxicities of the heart are highly relevant for patients with cancer in the thoracic region, risk stratification models for these toxicities are lacking. In this study, liquid, functional and imaging biomarkers are being investigated for their use in prediction of cardiac toxicity following R(CH)T for patients with thoracic malignancies.

NCT Number	NCT06986291
Lead Sponsor	Technische Universität Dresden
Conditions	Non-small Cell Lung Cancer, Esophageal Cancer, Breast Cancer Female
Enrollment	325 participants
Start Date	2025-08
Primary Completion	2034-12 (estimated)
Study Completion	2039-12 (estimated)
Updated on ClinicalTrials.gov	2025-05-29