Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico

The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing cardiovascular-related disparities in Puerto Rico. To this end, investigators will establish 'PROSPECT: Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic disease Trends', an island-wide, longitudinal population cohort of 2,500 adults (30-75 years) in PR recruited with a community-wide sampling strategy, and assessed in a network of several partner clinics across the island. The study will collect comprehensive data on multiple psychosocial, dietary, and food-related factors, CVD biological markers, and medical record data, with follow-up at 2-years, and will assess variations by urban-rural area and by timing before-after Maria.

NCT Number	NCT03794531
Lead Sponsor	Harvard School of Public Health (HSPH) Collaborators: National Heart, Lung, and Blood Institute (NHLBI), National Institute on Minority Health and Health Disparities (NIMHD), University of Massachusetts, Lowell, San Diego State University, Albert Einstein College of Medicine, Puerto Rico Consortium for Clinical Investigations
Conditions	Heart Diseases, Type2 Diabetes, Hypertension, Obesity, Dyslipidemias, Metabolic Syndrome, Cardiovascular Diseases, Chronic Disease +8 more
Enrollment	2,500 participants
Start Date	2019-03-01
Primary Completion	2029-04-30 (estimated)
Study Completion	2029-04-30 (estimated)
Updated on ClinicalTrials.gov	2026-05-05