Sponsor pipeline

Moderna clinical trial pipeline

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

What changed in the last 30 days

3 trials changed in the last 30 days: 0 stopped, 1 with a notable change, 2 with minor changes only.

Show 2 trials with minor changes only
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-10-13 NCT07870330 A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in… Phase 1 Not Yet Recruiting
2026-10-07 NCT07863635 A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing… Phase 4 Not Yet Recruiting

Active trials by phase

Phase 1
9
Phase 1/2
8
Phase 2
5
Phase 3
2
Phase 4
3
Not charted: 3 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 30

NCT IDTitleConditionStatusUpdated
Phase 4
NCT06585241 A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing… SARS-CoV-2 Recruiting 2026-03-27
NCT07863635 A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing… SARS-CoV-2 Not Yet Recruiting 2026-10-07
NCT07266558 A Study to Evaluate the Efficacy and Safety of mRNA-1283 and mRNA-1273 in Participants 50… SARS-CoV-2 Active, Not Recruiting 2026-09-28
Phase 3
NCT07496450 A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults Influenza Active, Not Recruiting 2026-08-11
NCT06592794 A Study to Investigate the Safety and Efficacy of mRNA-1403 in Participants ≥18 Years of… Acute Gastroenteritis Active, Not Recruiting 2026-05-13
Phase 2
NCT06735248 A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With… Multiple Sclerosis Recruiting 2026-06-15
NCT07808697 A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1283 in… SARS-CoV-2 Not Yet Recruiting 2026-09-09
NCT03897881 An Efficacy Study of Adjuvant Treatment With the Personalized Cancer Vaccine mRNA-4157… Melanoma Active, Not Recruiting 2026-09-08
NCT05683457 A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus… Cytomegalovirus Infection Active, Not Recruiting 2026-08-10
NCT07561294 A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1982 to… Lyme Disease Active, Not Recruiting 2026-08-03
Phase 1/2
NCT07116616 A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma Relapsed or Refractory Multiple Myeloma Recruiting 2026-09-23
NCT05533697 Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade… Advanced Solid Tumors Recruiting 2026-07-14
NCT05130437 A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants… Propionic Acidemia Recruiting 2026-03-23
NCT04159103 Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia Propionic Acidemia Recruiting 2026-01-22
NCT05295433 An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in… Methylmalonic Acidemia Recruiting 2025-12-23
NCT05164094 A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to… Epstein-Barr Virus Infection Active, Not Recruiting 2026-05-06
NCT05992935 Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1403 and… Norovirus Acute Gastroenteritis Active, Not Recruiting 2026-04-03
NCT05095727 A Study of mRNA-3745 in Adult and Pediatric Participants With Glycogen Storage Disease… Glycogen Storage Disease Active, Not Recruiting 2025-12-15
Phase 1
NCT06880549 A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer… Advanced Solid Tumors Recruiting 2026-10-13
NCT06655870 A Study to Investigate Safety and Tolerability of mRNA-0184 Administered Subcutaneously… Healthy Participants Recruiting 2026-09-15
NCT07764237 A Study to Investigate Safety, Reactogenicity, and Immunogenicity of mRNA-1365 (Profile… Respiratory Syncytial Virus (RSV) Recruiting 2026-08-19
NCT07478952 A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189 in Healthy Adults 18… Epstein-Barr Virus Recruiting 2026-03-24
NCT07870330 A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in… Seasonal Influenza Not Yet Recruiting 2026-10-13
NCT07737717 A Study to Investigate the Safety, Reactogenicity, and Immunogenicity of mRNA-1469… Ebola-Bundibugyo Virus Disease (Ebola-BDBV) Active, Not Recruiting 2026-09-24
NCT03313778 Safety, Tolerability, and Immunogenicity of mRNA-4157 Alone and in Combination in… Solid Tumors Active, Not Recruiting 2026-09-03

Disease areas by active trials

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