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Moderna clinical trial pipeline

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27 active trials 12 recruiting 2 Phase 3 3 disease areas 7 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-06

What changed in the last 30 days

2026-08-11
Primary completion pushed: 2026-08-01 → 2027-03-06
Completion pushed: 2026-08-01 → 2027-03-06
NCT05683457 A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus… · Phase 2
2026-08-21
Trial completed
NCT06067230 A Study to Investigate the Immunogenicity and Safety of mRNA-1345 Vaccine Targeting… · Phase 3
2026-08-12
Enrollment closed, study ongoing
NCT07496450 A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults · Phase 3
2026-08-20
Recruitment opened
NCT07764237 A Study to Investigate Safety, Reactogenicity, and Immunogenicity of mRNA-1365 (Profile… · Phase 1
2026-08-12
Recruitment opened
NCT07737717 A Study to Investigate the Safety, Reactogenicity, and Immunogenicity of mRNA-1469… · Phase 1
2026-08-11
Enrollment reopened
NCT06880549 A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer… · Phase 1

New trial filings, last 30 days

First postedTrialPhaseStatus
2026-08-13 NCT07764237 A Study to Investigate Safety, Reactogenicity, and Immunogenicity of mRNA-1365 (Profile… Phase 1 Recruiting

Active trials by phase

Phase 1
8
Phase 1/2
8
Phase 2
4
Phase 3
2
Phase 4
2
Not charted: 3 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 27

NCT IDTitleConditionStatusUpdated
Phase 4
NCT06585241 A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing… SARS-CoV-2 Recruiting 2026-03-27
NCT07266558 A Study to Evaluate the Efficacy and Safety of mRNA-1283 and mRNA-1273 in Participants 50… SARS-CoV-2 Active, Not Recruiting 2026-04-28
Phase 3
NCT07496450 A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults Influenza Active, Not Recruiting 2026-08-11
NCT06592794 A Study to Investigate the Safety and Efficacy of mRNA-1403 in Participants ≥18 Years of… Acute Gastroenteritis Active, Not Recruiting 2026-05-13
Phase 2
NCT06735248 A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With… Multiple Sclerosis Recruiting 2026-06-15
NCT05683457 A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus… Cytomegalovirus Infection Active, Not Recruiting 2026-08-10
NCT07561294 A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1982 to… Lyme Disease Active, Not Recruiting 2026-08-03
NCT03897881 An Efficacy Study of Adjuvant Treatment With the Personalized Cancer Vaccine mRNA-4157… Melanoma Active, Not Recruiting 2025-12-03
Phase 1/2
NCT07116616 A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma Relapsed or Refractory Multiple Myeloma Recruiting 2026-07-24
NCT05533697 Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade… Advanced Solid Tumors Recruiting 2026-07-14
NCT05130437 A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants… Propionic Acidemia Recruiting 2026-03-23
NCT04159103 Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia Propionic Acidemia Recruiting 2026-01-22
NCT05295433 An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in… Methylmalonic Acidemia Recruiting 2025-12-23
NCT05164094 A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to… Epstein-Barr Virus Infection Active, Not Recruiting 2026-05-06
NCT05992935 Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1403 and… Norovirus Acute Gastroenteritis Active, Not Recruiting 2026-04-03
NCT05095727 A Study of mRNA-3745 in Adult and Pediatric Participants With Glycogen Storage Disease… Glycogen Storage Disease Active, Not Recruiting 2025-12-15
Phase 1
NCT07764237 A Study to Investigate Safety, Reactogenicity, and Immunogenicity of mRNA-1365 (Profile… Respiratory Syncytial Virus (RSV) Recruiting 2026-08-19
NCT07737717 A Study to Investigate the Safety, Reactogenicity, and Immunogenicity of mRNA-1469… Ebola-Bundibugyo Virus Disease (Ebola-BDBV) Recruiting 2026-08-11
NCT06880549 A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer… Advanced Solid Tumors Recruiting 2026-08-10
NCT07478952 A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189 in Healthy Adults 18… Epstein-Barr Virus Recruiting 2026-03-24
NCT03313778 Safety, Tolerability, and Immunogenicity of mRNA-4157 Alone and in Combination in… Solid Tumors Active, Not Recruiting 2026-09-03
NCT05831111 A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1195, in 18- to… Epstein-Barr Virus Infection Active, Not Recruiting 2026-08-11
NCT05743881 A Safety, Tolerability, and Immunogenicity Study of mRNA-1345 and mRNA-1365 in… Respiratory Syncytial Virus Active, Not Recruiting 2026-06-26
NCT06655870 A Study to Investigate Safety and Tolerability of mRNA-0184 Administered Subcutaneously… Healthy Participants Active, Not Recruiting 2026-01-20
Not specified
NCT05769621 A Retrospective Study to Characterize Participants With Propionic Acidemia Propionic Acidemia Recruiting 2026-02-05
See all 27 active Moderna trials with filters →

Disease areas by active trials

Melanoma (1) · Multiple Myeloma (1) · Multiple Sclerosis (1)

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