Sponsor pipeline

Moderna clinical trial pipeline

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-20

What changed in the last 30 days

3 trials changed in the last 30 days: 0 stopped, 1 with a notable change, 2 with minor changes only.

Notable

MRNA-1283 and mRNA-1273 in Participants 50 to 64 Years of Age Without High-Risk Conditions for Severe Coronavirus Disease 2019 (COVID-19)

Primary endpoint(s) modified

ModernaTX, Inc.Phase 4 NCT07266558 Registry history of NCT07266558 on ClinicalTrials.gov (opens the registry)

Sep 28, 2026

Show 2 trials with minor changes only

Minor

Reactogenicity, and Immunogenicity of mRNA-1469 Vaccine to Prevent Ebola-Bundibugyo Virus Disease in Healthy Adult Participants

Enrollment closed, study ongoing

ModernaTX, Inc.Phase 1 NCT07737717 Registry history of NCT07737717 on ClinicalTrials.gov (opens the registry)

Sep 24, 2026
Minor

MRNA-2808 · Relapsed or Refractory Multiple Myeloma

Enrollment increased: 166 → 190 participants

ModernaTX, Inc.Phase 1/2 NCT07116616 Registry history of NCT07116616 on ClinicalTrials.gov (opens the registry)

Sep 23, 2026

Stopped: an ongoing trial was terminated, suspended or withdrawn.
Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
Minor: routine progress and housekeeping, such as sites added or enrollment closed.

New trial filings, last 30 days

First posted	Trial	Phase	Status
2026-10-13	NCT07870330 A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in…	Phase 1	Not Yet Recruiting
2026-10-07	NCT07863635 A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing…	Phase 4	Not Yet Recruiting

Active trials by phase

Phase 1		9
Phase 1/2		8
Phase 2		5
Phase 3		2
Phase 4		3

Not charted: 3 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Disease areas by active trials

Melanoma (2) · Heart Disease (1) · Multiple Myeloma (1) · Multiple Sclerosis (1)

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