| Detected | Trial | Change |
|---|---|---|
| 2026-08-01 | NCT06985147 A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV) |
Enrollment closed, study ongoing |
| 2026-07-21 | NCT05320198 Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic… |
Primary endpoint(s) modified |
| 2026-07-21 | NCT05320198 Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic… |
Trial sites expanded: 25 -> 28 locations |
| 2026-07-21 | NCT05320198 Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic… |
date change Primary completion pushed: 2026-09 -> 2027-05 |
| 2026-07-21 | NCT05320198 Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic… |
date change Completion pushed: 2026-09 -> 2027-06 |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06910358 | Study of Bitopertin in Participants With EPP or XLP (APOLLO) | Erythropoietic Protoporphyria (EPP) | Active, Not Recruiting |
| Phase 2/3 | |||
| NCT05883748 | HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability… | Erythropoietic Protoporphyria | Enrolling by Invitation |
| Phase 2 | |||
| NCT07368972 | Study of DISC-0974-201 in Participants With IBD and Anemia | Inflammatory Bowel Disease (IBD) | Recruiting |
| NCT06985147 | A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV) | Polycythemia Vera (PV) | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT05320198 | Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic… | Myelofibrosis; Anemia | Recruiting |
| Phase 1 | |||
| NCT07187973 | A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD) | Sickle Cell Disease | Recruiting |