Clinical Trial

A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

Active, Not Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
This open-label, multicenter, within-participant dose escalation study examining up to 2 dose levels of DISC-3405 will assess the safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics of DISC-3405 in participants with polycythemia vera (PV).
Protocol Amendment History 1 change
critical Enrollment closed, study ongoing 2026-08-01
Trial Details
NCT Number NCT06985147
Lead Sponsor Disc Medicine, Inc
Conditions Polycythemia Vera (PV)
Enrollment 60 participants
Start Date 2025-08-12
Primary Completion 2027-02 (estimated)
Study Completion 2029-02 (estimated)
Updated on ClinicalTrials.gov 2026-07-31