Sponsor Pipeline

Denali Therapeutics Inc. Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
9
Active Trials
3
Recruiting
2
Phase 3
3
Disease Areas
What Changed in the Last 30 Days
First PostedNew Trial FilingPhaseStatus
2026-08-11 NCT07758595 A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL921 in… Phase 1 Not Yet Recruiting
Active Trials by Phase
Phase 2/3
2
Phase 2
1
Phase 1/2
3
Phase 1
3
Active Trials
NCT IDTitleConditionStatus
Phase 2/3
NCT05371613 A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase… Mucopolysaccharidosis II Recruiting
NCT06075537 An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp… Mucopolysaccharidosis II Enrolling by Invitation
Phase 2
NCT06602193 Safety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated… Parkinson Disease Active, Not Recruiting
Phase 1/2
NCT04251026 A Study of Tividenofusp Alfa (DNL310) in Pediatric Participants With Hunter Syndrome Mucopolysaccharidosis II Active, Not Recruiting
NCT05262023 A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of… Frontotemporal Dementia Active, Not Recruiting
NCT06181136 Study of DNL126 in Pediatric Participants With Mucopolysaccharidosis Type IIIA… Mucopolysaccharidosis Type IIIA Active, Not Recruiting
Phase 1
NCT07354724 A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult… Late-onset Pompe Disease Recruiting
NCT07328451 A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of… Alzheimer Disease, Early Onset Recruiting
NCT07758595 A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL921 in… Alzheimer's Disease Not Yet Recruiting
Disease Areas
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