Sponsor pipeline

Denali Therapeutics Inc. clinical trial pipeline

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

Active trials by phase

Phase 1
3
Phase 1/2
3
Phase 2
1
Phase 2/3
2

Active trials

NCT IDTitleConditionStatusUpdated
Phase 2/3
NCT05371613 A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase… Mucopolysaccharidosis II Active, Not Recruiting 2026-09-09
NCT06075537 An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp… Mucopolysaccharidosis II Enrolling by Invitation 2026-06-11
Phase 2
NCT06602193 Safety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated… Parkinson Disease Active, Not Recruiting 2026-05-27
Phase 1/2
NCT06181136 Study of DNL126 in Pediatric Participants With Mucopolysaccharidosis Type IIIA… Mucopolysaccharidosis Type IIIA Active, Not Recruiting 2026-07-13
NCT05262023 A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of… Frontotemporal Dementia Active, Not Recruiting 2026-01-15
NCT04251026 A Study of Tividenofusp Alfa (DNL310) in Pediatric Participants With Hunter Syndrome Mucopolysaccharidosis II Active, Not Recruiting 2025-08-07
Phase 1
NCT07758595 A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL921 in… Alzheimer's Disease Recruiting 2026-08-20
NCT07354724 A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult… Late-onset Pompe Disease Recruiting 2026-08-17
NCT07328451 A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of… Alzheimer Disease, Early Onset Recruiting 2026-07-01

Disease areas by active trials

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