| Detected | Trial | Change |
|---|---|---|
| 2026-08-07 | NCT04179643 AB-1002 in Patients With Class III Heart Failure |
Trial completed |
| 2026-08-07 | NCT04179643 AB-1002 in Patients With Class III Heart Failure |
Enrollment reduced: 17 -> 11 participants |
| 2026-08-07 | NCT04179643 AB-1002 in Patients With Class III Heart Failure |
date change Completion moved earlier: 2026-09-30 -> 2026-07-23 |
| 2026-07-28 | NCT07215403 Prescriptive Infusion Algorithm (PIA) |
Trial sites expanded: 1 -> 4 locations |
| 2026-07-28 | NCT07215403 Prescriptive Infusion Algorithm (PIA) |
date change Primary completion pushed: 2027-12-30 -> 2028-04-30 |
| 2026-07-28 | NCT07215403 Prescriptive Infusion Algorithm (PIA) |
date change Completion pushed: 2028-03-01 -> 2028-11-01 |
| 2026-07-28 | NCT05699460 Pre-Gene Therapy Study in Parkinson's Disease and Multiple System Atrophy |
Trial completed |
| 2026-07-28 | NCT05699460 Pre-Gene Therapy Study in Parkinson's Disease and Multiple System Atrophy |
Enrollment reduced: 150 -> 73 participants |
| 2026-07-21 | NCT07282847 A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene)… |
Primary endpoint(s) modified |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 2 | |||
| NCT06285643 | A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD) | Parkinson Disease | Recruiting |
| NCT05598333 | Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA… | Congestive Heart Failure | Active, Not Recruiting |
| NCT07215403 | Prescriptive Infusion Algorithm (PIA) | PARKINSON DISEASE (Disorder) | Not Yet Recruiting |
| Phase 1/2 | |||
| NCT05230459 | A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic… | Limb Girdle Muscular Dystrophy | Recruiting |
| NCT07282847 | A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene)… | Pompe Disease (Late-onset) | Recruiting |
| Not specified | |||
| NCT07081841 | AB-1005 Long-Term Follow-up Study | Parkinson's Disease | Enrolling by Invitation |