Drug Pipeline

Tislelizumab Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
81
Active Studies
41
Recruiting
18
Phase 3
10
Top Sponsors
25
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-10 NCT07468071
Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit…
Recruitment opened
2026-06-09 NCT06422520
A First-in-Human Study of BGB-C354 Alone and in Combination With Tislelizumab in…
Trial completed
2026-06-09 NCT06422520
A First-in-Human Study of BGB-C354 Alone and in Combination With Tislelizumab in…
Enrollment reduced: 120 -> 63 participants
2026-06-09 NCT06422520
A First-in-Human Study of BGB-C354 Alone and in Combination With Tislelizumab in…
date change Primary completion moved earlier: 2026-12-01 -> 2026-05-15
2026-06-09 NCT06422520
A First-in-Human Study of BGB-C354 Alone and in Combination With Tislelizumab in…
date change Completion moved earlier: 2027-01-31 -> 2026-05-15
2026-06-05 NCT06596473
A Study of BG-C477 in Participants With Advanced Solid Tumors
Trial sites expanded: 49 -> 52 locations
2026-06-04 NCT06427941
A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without…
Trial sites expanded: 29 -> 46 locations
2026-06-04 NCT04164199
Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With…
Trial completed
2026-06-04 NCT04164199
Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With…
date change Primary completion moved earlier: 2026-07 -> 2026-05-23
2026-06-04 NCT04164199
Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With…
date change Completion moved earlier: 2026-07 -> 2026-05-23
2026-06-04 NCT06585488
A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in…
Trial terminated — check why_stopped for reason
2026-06-04 NCT06585488
A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in…
critical why stopped: null → "The Sponsor has made the decision to terminate this study due to the lack of promising efficacy, internal prioritization, and highly competitive landscape."
2026-06-04 NCT06585488
A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in…
Enrollment reduced: 514 -> 47 participants
2026-06-04 NCT06585488
A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in…
Sponsor changed: BeiGene -> BeOne Medicines
2026-06-04 NCT06585488
A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in…
date change Primary completion moved earlier: 2026-12 -> 2026-04-23
2026-06-04 NCT06585488
A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in…
date change Completion moved earlier: 2026-12 -> 2026-04-23
2026-05-30 NCT07043400
A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus…
Trial sites expanded: 86 -> 93 locations
2026-05-28 NCT07414836
A First-in-Human Study of BG-C0979 in Adults With Advanced Solid Tumors
Trial sites expanded: 4 -> 8 locations
2026-05-27 NCT06596473
A Study of BG-C477 in Participants With Advanced Solid Tumors
Trial sites expanded: 41 -> 49 locations
2026-05-15 NCT06427941
A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without…
Primary endpoint(s) modified
Showing 20 of 25 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-08 NCT07633873 SYS6010 Combined With Enlonstobart Versus Immunotherapy+ Platinum-based Chemotherapy for… Phase 3 Not Yet Recruiting
2026-05-27 NCT07609121 Hypofractionated Chemoradiotherapy With Tislelizumab and Surufatinib for Unresectable… Phase 2 Not Yet Recruiting
2026-05-27 NCT07609667 SKB315 in Combination Therapy in Patients With Advanced or Metastatic GC/ GEJ… Phase 2 Not Yet Recruiting
2026-05-22 NCT07601737 Nimotuzumab Combined With PD-1 Inhibitors and Chemotherapy in the Treatment of Locally… Phase 2 Recruiting
Active Studies by Phase
Phase 3
15
Phase 2/3
3
Phase 2
34
Phase 1/2
7
Phase 1
19
Early Phase 1
2
Not specified
1
Active Trials — top 25 of 81
NCT IDTitleConditionStatus
Phase 3
NCT07315750 A Study of Disitamab Vedotin Combined With Trastuzumab and Tislelizumab Versus… Gastric Carcinoma Recruiting
NCT06745908 Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and… NSCLC Stage IV Recruiting
NCT07043400 A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus… Metastatic Gastric Adenocarcinoma Recruiting
NCT06206733 ASKB589 in Combination With CAPOX and PD-1 Inhibitor in Patients With Advanced or… Gastroesophageal Junction Adenocarcinoma Active, Not Recruiting
NCT07373990 Short-course Tislelizumab Combined With Chemoradiotherapy for Nasopharyngeal Carcinoma Nasopharyngeal Cancinoma (NPC) Not Yet Recruiting
NCT07383116 Phase III Clinical Study of HB0025 Combined With Chemotherapy Versus Tislelizumab… Non Squamous Non-small Cell Lung Cancer Not Yet Recruiting
NCT07385703 Clinical Study on the Efficacy and Safety of LM-302 Injection Combined With Tislelizumab… Adenocarcinoma Not Yet Recruiting
NCT07475026 A Study of Neoadjuvant Tislelizumab Plus Lenvatinib in Resectable HCC at High Risk of… HCC - Hepatocellular Carcinoma Not Yet Recruiting
NCT04379635 Comparing the Efficacy and Safety of a New Additional Treatment With Tislelizumab in… Non Small Cell Lung Cancer Active, Not Recruiting
NCT07502300 A Study Comparing BL-B01D1 Combined With Tislelizumab Versus Platinum-containing… Extensive-stage Small-cell Lung Cancer Not Yet Recruiting
NCT03967977 Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for… Urothelial Carcinoma Active, Not Recruiting
NCT05152147 A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in… Gastric Neoplasms Active, Not Recruiting
NCT05211232 Neoadjuvant and Adjuvant Tislelizumab for Nasopharyngeal Carcinoma Nasopharyngeal Carcinoma Active, Not Recruiting
NCT06914011 Circulating Tumor DNA MRD-Guided Adjuvant Therapy for Curatively Resected Locally… Esophageal Cancer Not Yet Recruiting
NCT07633873 SYS6010 Combined With Enlonstobart Versus Immunotherapy+ Platinum-based Chemotherapy for… Non-Small Cell Lung Cancer Not Yet Recruiting
Phase 2/3
NCT06312982 A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally… Locally Advanced Rectal Carcinoma Recruiting
NCT06563245 Brentuximab Vedotin for Newly Diagnosed cHL in Chinese CAYA Based on PET/CT Assessment Classical Hodgkin Lymphoma Recruiting
NCT07554456 A Study of BL-B01D1 in Combination With Tislelizumab ±5-Fluorouracil Versus… Esophageal Squamous Cell Carcinoma Not Yet Recruiting
Phase 2
NCT07050056 Tislelizumab Combined With Thoracic Radiotherapy as Neoadjuvant Therapy for Resectable… Resectable NSCLC Recruiting
NCT07330037 TALENT Study: Phase II Trial of Adjuvant L-TIL Plus Tislelizumab in Resectable NSCLC… NSCLC Recruiting
NCT05366829 Tislelizumab Consolidation After Liver-Directed Therapy for Hepatocellular Carcinoma Carcinoma, Hepatocellular Recruiting
NCT06764355 Neoadjuvant Immunochemotherapy and Chemoradiotherapy Followed by Surgery for Advanced… ESCC Recruiting
NCT07370337 Induction Chemotherapy Combined With Tislelizumab for Locally Advanced Squamous Cell… Squamous Cell Carcinoma of External Auditory Canal Recruiting
NCT07039162 Study of Tislelizumab Combined With Chemoradiotherapy and Surgery for Unresectable… Esophageal Squamous Cell Carcinoma (ESCC) Recruiting
NCT07120282 Study to Evaluate the Efficacy and Safety of Adjuvant Tislelizumab in High-Risk Stage I… Lung Cancer (NSCLC) Recruiting
Sponsors Running Tislelizumab Trials
Disease Areas
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