| Detected | Trial | Change |
|---|---|---|
| 2026-06-03 | NCT07570069 Effects of Efavirenz on the Pharmacokinetics of Suzetrigine in Healthy Participants |
Recruitment opened |
| 2026-05-20 | NCT07231419 Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic… |
Trial sites expanded: 66 -> 75 locations |
| 2026-05-14 | NCT07378865 Evaluation of the Excretion of Suzetrigine Into Breast Milk in Healthy Lactating Female… |
Primary endpoint(s) modified |
| 2026-05-14 | NCT07538570 Evaluation of Pain Treatment After Total Knee Arthroplasty |
Recruitment opened |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-03 | NCT07624526 Role of Suzetrigine as a Part of a Multimodal Regimen to Reduce Pain and Opioid Use After… | Phase 4 | Not Yet Recruiting |
| 2026-05-22 | NCT07600697 Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic… | Phase 4 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT07538570 | Evaluation of Pain Treatment After Total Knee Arthroplasty | Pain | Recruiting |
| NCT07355166 | Suzetrigine Versus Usual-care Opioids for Postop Pain in Sports | Postoperative Pain Management | Not Yet Recruiting |
| NCT07534709 | Suzetrigine for Opioid-Free Recovery After Cesarean Delivery | Cesarean Delivery | Not Yet Recruiting |
| NCT07463430 | Suzetrigine for Non-Mastectomy Breast Surgery | Pain, Acute Postoperative | Enrolling by Invitation |
| NCT07575230 | Suzetrigine vs Norco-postoperative Mohs Pain | Cutaneous Tumors | Enrolling by Invitation |
| NCT07600697 | Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic… | Pelvic Organ Prolapse (POP) | Not Yet Recruiting |
| NCT07624526 | Role of Suzetrigine as a Part of a Multimodal Regimen to Reduce Pain and Opioid Use After… | Knee Arthritis | Not Yet Recruiting |
| Phase 3 | |||
| NCT07548385 | Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN | Total Knee Replacement Surgery | Recruiting |
| NCT06628908 | Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic… | Diabetic Peripheral Neuropathic Pain | Recruiting |
| NCT07539623 | Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery | Bariatric Surgery | Recruiting |
| NCT07231419 | Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic… | Diabetic Peripheral Neuropathic Pain | Recruiting |
| NCT07226700 | Suzetrigine in Total Hip Arthroplasty | Total Hip Arthroplasty (THA) | Recruiting |
| NCT07357376 | Evaluating Suzetrigine for Pain Control Following TKA | Postoperative Pain Following Knee Arthroplasty | Not Yet Recruiting |
| NCT07525219 | Suzetrigine Frame Trial Comparing Suzetrigine and Acetaminophen | Analgesic Efficacy | Not Yet Recruiting |
| NCT06696443 | Evaluation of the Long-term Safety and Effectiveness of Suzetrigine (SUZ) in Participants… | Diabetic Peripheral Neuropathic Pain | Active, Not Recruiting |
| Phase 1 | |||
| NCT07378865 | Evaluation of the Excretion of Suzetrigine Into Breast Milk in Healthy Lactating Female… | Pain | Recruiting |
| NCT07570069 | Effects of Efavirenz on the Pharmacokinetics of Suzetrigine in Healthy Participants | Pain | Recruiting |
| Early Phase 1 | |||
| NCT07511400 | The Role of NaV1.8 in Human Pain Models | Pain | Recruiting |