Clinical Trial

Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery

Study acronym: SMOOTH-SURG
Recruiting Phase 3
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Summary
This is prospective, randomized study. The purpose of this study is to evaluate whether the addition of Suzetrigine to well established multimodal pain regimen for participants undergoing bariatric patients undergoing weight-loss surgery and cardiac patients undergoing sternotomy will reduce post-operative opioid consumption and pain scores.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-04-13.
Trial Details
NCT Number NCT07539623
Lead Sponsor Icahn School of Medicine at Mount Sinai
Conditions Bariatric Surgery, Cardiac Surgery With Sternotomy, Post-operative Pain
Enrollment 235 participants
Start Date 2026-05-01
Primary Completion 2026-12-22 (estimated)
Study Completion 2026-12-22 (estimated)
Updated on ClinicalTrials.gov 2026-05-14