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Role of Suzetrigine as a Part of a Multimodal Regimen to Reduce Pain and Opioid Use After Total Knee Arthroplasty

StatusNot Yet Recruiting
PhasePhase 4
Started2026-07
View on ClinicalTrials.gov ↗
This study is a prospective, single-arm interventional trial enrolling patients undergoing total knee arthroplasty (TKA) for knee arthritis. All participants will receive Suzetrigine (brand name Journavx by Vertex Pharma) as part of a standardized multimodal perioperative analgesic regimen in addition to standard of care.
Trial Details
NCT Number NCT07624526
Lead Sponsor Emory University
Collaborators: Vertex Pharmaceuticals Incorporated
Conditions Knee Arthritis, Knee Osteoarthritis
Enrollment 75 participants
Start Date 2026-07
Primary Completion 2028-08 (estimated)
Study Completion 2028-08 (estimated)
Updated on ClinicalTrials.gov 2026-06-03