Drug Pipeline

Sintilimab Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
55
Active Studies
33
Recruiting
13
Phase 3
10
Top Sponsors
1
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-16 NCT07394387
Neoadjuvant Study of HIFU With or Without PD-1 Inhibitors Followed by Abraxane Plus…
Enrollment increased: 39 -> 58 participants
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-11 NCT07643623 Neoadjuvant and Adjuvant Therapy Studies of Sintilimab Combined With Chemotherapy With or… Phase 2/3 Not Yet Recruiting
2026-06-10 NCT07638631 Ipilimumab (N01) Plus Sintilimab and Modified XELOX as Conversion Therapy in Unresectable… Phase 2 Not Yet Recruiting
2026-05-28 NCT07612137 Study of IBI3005 Combination Therapy in Participants With Unresectable, Locally Advanced… Phase 1/2 Not Yet Recruiting
2026-05-19 NCT07594925 Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for… Phase 2 Recruiting
Active Studies by Phase
Phase 4
1
Phase 3
11
Phase 2/3
2
Phase 2
29
Phase 1/2
2
Phase 1
5
Not specified
5
Active Trials — top 25 of 55
NCT IDTitleConditionStatus
Phase 4
NCT03753555 The Effect of InTensive Statin in Ischemic Stroke With inTracranial Atherosclerotic… Stroke, Ischemic Recruiting
Phase 3
NCT05855200 Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III… Colonic Neoplasms Recruiting
NCT04495088 Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With… Rectal Cancer Recruiting
NCT07459296 Becotatug Vedotin Plus Sintilimab in Locoregionally Advanced NPC Nasopharyngeal Carcinoma (NPC) Recruiting
NCT06497985 A Study of Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR… Colorectal Cancer Recruiting
NCT06346197 Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric… Gastric Cancer Recruiting
NCT05357846 PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy Plus Surgery for Locally… Squamous Cell Esophageal Carcinoma Recruiting
NCT06618664 A Clinical Study of SHR-8068 Combined With Adebrelimab and Bevacizumab Versus Sintilimab… Advanced Hepatocellular Carcinoma Recruiting
NCT07306663 Sintilimab Combined With Chemotherapy Induction Therapy Followed by CCRT vs. CCRT for… Esophageal Cancer Active, Not Recruiting
NCT05171660 Combination With Sintilimab and XELOX+Bevacizumab as 1st Line Therapy in RAS-mutant… Colorectal Cancer Stage IV Active, Not Recruiting
NCT07537946 Local Consolidation After Sintilimab Plus Lenvatinib for Metastatic Liver Cancer Hepatocellular Carcinoma (HCC) Not Yet Recruiting
NCT05890742 A Clinical Trial Evaluating the Efficacy and Safety of IBI310 in Combination With… MSI-H Active, Not Recruiting
Phase 2/3
NCT07490262 A Study to Evaluate the Efficacy and Safety of IBI310 and Sintilimab Combination Therapy… Hepatocellular Carcinoma (HCC) Recruiting
NCT07643623 Neoadjuvant and Adjuvant Therapy Studies of Sintilimab Combined With Chemotherapy With or… Resectable Gastric/Gastroesophageal Junction Adenocarcinoma Not Yet Recruiting
Phase 2
NCT07120698 Adaptive Adjuvant Sintilimab Therapy Guided by MRD (ADAPT Lung) NSCLC (Non-small Cell Lung Cancer) Recruiting
NCT07077512 Relmacabtagene Autoleucel Combined With Sintilimab for Relapsed/Refractory B-cell Lymphoma Large B Cell Diffuse Lymphoma Recruiting
NCT07400302 Sintilimab Combined With Chemotherapy for Adjuvant Treatment of Mucosal Melanoma After… Mucosal Melanoma Recruiting
NCT07468630 Tolecizumab Plus Chemoimmunotherapy for pMMR/MSS Locally Advanced Colon Adenocarcinoma Colon Adenocarcinoma Recruiting
NCT07492615 A Clinical Study of Sintilimab Combined With Chemothrapy Versus Chemotherapy as Adjuvant… Gastric Cancer or Gastroesophageal Junction Adenocarcinoma Recruiting
NCT07506109 A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in… BRAF V600E Recruiting
NCT07518602 Efficacy and Safety of Chidamide+Sintilimab+Bev as Second-Line Therapy in Advanced… Extrapulmonary Neuroendocrine Carcinoma (EP-NEC) Recruiting
NCT03872661 Neoadjuvant IBI308, Bevacizumab, Plus Pemetrexed and Carboplatin Followed by Surgery in… Lung Cancer Stage III Recruiting
NCT06860490 HAIC Combined With Sintilimab Plus Bevacizumab Biosimilar for Advanced Hepatocellular… Hepatocellular Carcinoma (HCC) Recruiting
NCT06204094 Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS… Locally Advanced Rectal Cancer Recruiting
NCT07309952 Neoadjuvant SBRT Followed by Sintilimab Plus Chemotherapy for N3-Positive NSCLC Locally Advanced Non-Small Cell Lung Cancer Recruiting
Sponsors Running Sintilimab Trials
Disease Areas
Get alerts when Sintilimab trials change
Status changes, date slips, and new filings — detected daily, delivered to your inbox.
Start monitoring free