Drug Pipeline

SHR-A1811 Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
28
Active Studies
10
Recruiting
3
Phase 3
10
Top Sponsors
1
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT07560475
Exploratory Study of SHR-A1811 Via Different Administration Routes in Patients
Trial arms changed: 2 -> 3
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-08 NCT07631884 Exploratory Study on the Efficacy and Safety of Trastuzumab Rezetecan in the Treatment of… Phase 2 Not Yet Recruiting
2026-06-05 NCT07630077 Trastuzumab Rezetecan(SHR-A1811) Combined With Ivonescimab (AK112) in Locally Advanced or… Phase 2 Not Yet Recruiting
2026-06-05 NCT07630103 Efficacy and Safety of Trastuzumab Rezetecan or Trastuzumab Deruxtecan in Advanced Breast… Phase 2 Not Yet Recruiting
2026-06-01 NCT07618923 Neoadjuvant Dalpiciclib + AI → SHR-A1811 for HR+/HER2-Low Breast Cancer Phase 2 Not Yet Recruiting
2026-05-20 NCT07600164 Real-world Study of Pyrotinib-containing Regimens of Advanced HER2-positive Breast Cancer Phase 4 Not Yet Recruiting
2026-05-15 NCT07589699 Trastuzumab Rezetecan (T-DXh) in HER2+ Breast Cancer With Non-pCR After TCbHP Phase 4 Not Yet Recruiting
Active Studies by Phase
Phase 4
2
Phase 3
3
Phase 2
21
Not specified
2
Active Trials — top 25 of 28
NCT IDTitleConditionStatus
Phase 4
NCT07589699 Trastuzumab Rezetecan (T-DXh) in HER2+ Breast Cancer With Non-pCR After TCbHP Breast Cancer Not Yet Recruiting
NCT07600164 Real-world Study of Pyrotinib-containing Regimens of Advanced HER2-positive Breast Cancer HER2 + Breast Cancer Not Yet Recruiting
Phase 3
NCT06430437 A Study of SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic… Non-Small Cell Lung Cancer With HER2- Mutations Recruiting
NCT06828354 A Study of SHR-A1811 in Subjects With Ovarian Cancer Ovarian Cancer Recruiting
NCT07382687 Famitinib Combined With SHR-A1811, Versus SHR-A1811 for CDK4/6 Inhibitors-resistent… Breast Cancer Not Yet Recruiting
Phase 2
NCT07309770 Trastuzumab Rezetecan in Advanced Solid Tumors Refractory to Standard Therapies Urachal Cancer Recruiting
NCT07340398 Neoadjuvant Trastuzumab-rezetecan Plus Pertuzumab or Nab-Paclitaxel, Carboplatin… HER2-positive Early Breast Cancer Recruiting
NCT07203729 The Efficacy and Safety of Trastuzumab Rezetecan (SHR-A1811) in HER2-Low… HER2-Low Unresectable/Metastatic Breast Cancer Complicated With Visceral Crisis Recruiting
NCT05769010 Study of SHR-A1811 in HER2-expression Advanced Breast Cancer With Brain Metastases Metastatic Breast Cancer Recruiting
NCT06649331 Platform Study of ADC Rechallenge in ADC-treated Metastatic Breast Cancer Advanced Breast Cancer Recruiting
NCT07241793 Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in… Urothelial Carcinoma Recruiting
NCT07497386 A Trial of Trastuzumab Rezetecan in Unresectable Locally Recurrent/Metastatic Breast… Unresectable Locally Recurrent Breast Cancer Recruiting
NCT05582499 Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study… Breast Neoplasm Recruiting
NCT07305246 Clinical Study of SHR-A1811 With or Without Letrozole in Neoadjuvant Therapy for… Breast Cancer Not Yet Recruiting
NCT07317778 Chemotherapy With or Without Adebrelimab and T-DXh as Neoadjuvant Therapy for HR+/HER2… Breast Cancer Early Stage Breast Cancer (Stage 1-3) Not Yet Recruiting
NCT07416253 Trastuzumab Rezetecan vs Trastuzumab Deruxtecan in the Neoadjuvant Treatment of HER2… Breast Cancer Not Yet Recruiting
NCT07417241 SHR-A1811 vs Pyrotinib/Capecitabine in Trastuzumab-Resistant HER2+ Advanced Breast… Breast Cancer Not Yet Recruiting
NCT07466303 Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for… Breast Cancer Not Yet Recruiting
NCT07466927 Study of Multi-mode Thermal Therapy Combined With Immunotherapy In Patients With… HER2-negative Breast Cancer Not Yet Recruiting
NCT05924256 A Phase II Study of Advanced Salivary Gland Carcinoma Based on Molecular Typing Advanced Salivary Gland Carcinoma Active, Not Recruiting
NCT07528898 Neoadjuvant SHR-A1811 Combined With Pertuzumab in HER2-Positive Breast Cancer: An… Breast Cancer Not Yet Recruiting
NCT07630077 Trastuzumab Rezetecan(SHR-A1811) Combined With Ivonescimab (AK112) in Locally Advanced or… Non Small Cell Lung Cancer Not Yet Recruiting
NCT07630103 Efficacy and Safety of Trastuzumab Rezetecan or Trastuzumab Deruxtecan in Advanced Breast… Advanced Breast Cancer Not Yet Recruiting
NCT07631884 Exploratory Study on the Efficacy and Safety of Trastuzumab Rezetecan in the Treatment of… Solid Tumors Not Yet Recruiting
NCT07560475 Exploratory Study of SHR-A1811 Via Different Administration Routes in Patients HER2positive Not Yet Recruiting
Sponsors Running SHR-A1811 Trials
Disease Areas
Get alerts when SHR-A1811 trials change
Status changes, date slips, and new filings — detected daily, delivered to your inbox.
Start monitoring free