Study of Multi-mode Thermal Therapy Combined With Immunotherapy In Patients With HER2-negative Breast Cancer With Liver Metastases

This is a prospective, open-label, phase II platform trial. The purpose of this study is to test the safety and effectiveness of multi-mode thermal therapy combined with immunotherapy in patients with HER2-negative breast cancer with liver metastases who had previously received systemic therapy

NCT Number	NCT07466927
Lead Sponsor	Fudan University
Conditions	HER2-negative Breast Cancer
Enrollment	30 participants
Start Date	2026-03-15
Primary Completion	2028-01-15 (estimated)
Study Completion	2029-01-15 (estimated)
Updated on ClinicalTrials.gov	2026-03-12