Drug Pipeline

Letermovir Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
14
Active Studies
12
Recruiting
5
Phase 3
10
Top Sponsors
Active Studies by Phase
Phase 4
2
Phase 3
5
Phase 2
2
Phase 1
3
Not specified
2
Active Trials
NCT IDTitleConditionStatus
Phase 4
NCT07235683 Combination Letermovir and Standard of Care Antiviral for Enhanced Antiviral Response in… CMV Recruiting
NCT07571135 Letermovir vs Valganciclovir in CMV R+ Kidney Transplant CMV Infection Not Yet Recruiting
Phase 3
NCT06334497 Letermovir-based Dual Therapy for Treatment of Cytomegalovirus Infections Cytomegalovirus Infection Recruiting
NCT05446571 Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Versus… Pregnant Women Recruiting
NCT05711667 A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell… Hematopoietic and Lymphoid Cell Neoplasm Recruiting
NCT06407232 Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients Cytomegalovirus Infections Recruiting
NCT06001320 De-novo Initiation of Letermovir vs Valganciclovir for Cytomegalovirus Prophylaxis in AA… Kidney Transplant; Complications Active, Not Recruiting
Phase 2
NCT06575374 Single Arm Pilot Trial of Letermovir for CMV Prophy in CAR T Cell Cell Therapy Recruiting
NCT06066957 Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients Cytomegalovirus Infections Recruiting
Phase 1
NCT07020533 A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the… Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive Recruiting
NCT06118515 A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital… Congenital Cytomegalovirus Infection Recruiting
NCT07199465 A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney… Cytomegalovirus Prophylaxis Recruiting
Not specified
NCT07488728 Letermovir Prophylaxis in Children With EBV-Positive T/NK-Cell Lymphoproliferative… EBV-associated T/NK-cell Lymphoproliferative Diseases Recruiting
NCT06639854 The Use of Cytomegalovirus Cell Mediated Immunity to Optimize the Duration of Letermovir… Cytomegalovirus Cell Mediated Immunity Recruiting
Sponsors Running Letermovir Trials
Assistance Publique - Hôpitaux de Paris (2) M.D. Anderson Cancer Center (2) Children's Oncology Group (1) Virginia Commonwealth University (1) University of Pennsylvania (1) National Institute of Allergy and Infectious Diseases (NIAID) (1) University of Wisconsin, Madison (1) City of Hope Medical Center (1) Merck Sharp & Dohme LLC (1) University Health Network, Toronto (1)
Disease Areas
Leukemia (1) Acute Myeloid Leukemia (AML) (1) Acute Lymphoblastic Leukemia (ALL) (1) Chronic Lymphocytic Leukemia (CLL) (1) Chronic Myeloid Leukemia (CML) (1) Non-Hodgkin Lymphoma (1) Hodgkin Lymphoma (1) Myelodysplastic Syndromes (MDS) (1) Myelofibrosis (1)
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