Drug Pipeline

Glofitamab Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
47
Active Studies
27
Recruiting
3
Phase 3
10
Top Sponsors
7
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-05 NCT07528352
External Beam Radiotherapy Followed by Bispecific Antibody Therapy for…
Recruitment opened
2026-06-05 NCT07528352
External Beam Radiotherapy Followed by Bispecific Antibody Therapy for…
date change Primary completion pushed: 2030-05 -> 2030-06
2026-06-05 NCT07528352
External Beam Radiotherapy Followed by Bispecific Antibody Therapy for…
date change Completion pushed: 2031-05 -> 2031-06
2026-06-04 NCT06994169
Glofitamab in Real Life
date change Completion pushed: 2026-07-30 -> 2026-12-30
2026-05-30 NCT04077723
A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of…
Trial sites reduced: 44 -> 35 locations
2026-05-27 NCT04889716
CAR-T Followed by Bispecific Antibodies
Primary endpoint(s) modified
2026-05-27 NCT04889716
CAR-T Followed by Bispecific Antibodies
Enrollment reduced: 42 -> 23 participants
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-08 NCT07634289 Radiotherapy in Combination With Glofitamab in Relapsed/Refractory Diffuse Large B Cell… Phase 2 Not Yet Recruiting
2026-05-29 NCT07613788 Rimegepant Plus Glofitamab and CD19 CAR-T Therapy in R/R LBCL Phase 2 Not Yet Recruiting
2026-05-20 NCT07599423 A Study of Glofitamab Plus GemOx Compared With Standard of Care in Patients With… Phase 2 Not Yet Recruiting
2026-05-19 NCT07594899 AI-Driven Treatment Strategy vs Pola-R-CHP in Untreated LBCL Phase 2 Not Yet Recruiting
Active Studies by Phase
Phase 3
3
Phase 2
25
Phase 1/2
7
Phase 1
8
Early Phase 1
1
Not specified
3
Active Trials — top 25 of 47
NCT IDTitleConditionStatus
Phase 3
NCT06084936 A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in… Lymphoma Recruiting
NCT06047080 An Open-Label Study Comparing Glofitamab and Polatuzumab Vedotin + Rituximab… Large B-Cell Lymphoma Active, Not Recruiting
NCT04408638 A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs… Diffuse Large B-cell Lymphoma Active, Not Recruiting
Phase 2
NCT06054776 Acalabrutinib, Obinutuzumab, and Glofitamab for the Treatment of Relapsed or Refractory… Mantle Cell Lymphoma Recruiting
NCT06043674 Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or… Chronic Lymphocytic Leukemia Recruiting
NCT06213311 A Study of Axicabtagene Ciloleucel and Glofitamab as Second-Line Therapy for Relapsed or… B Cell Lymphoma Recruiting
NCT06558604 Phase II Study of Glofitamab With Venetoclax +/- Zanubrutinib in High-risk Mantle-cell… Lymphoma, Mantle-Cell Recruiting
NCT05800366 A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients With High-risk Diffuse… Lymphoma Recruiting
NCT07460362 Glofitamab Combined With Lenalidomide in High Risk Patients With Relapsed or Refractory… MCL Recruiting
NCT06252675 Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma Mantle Cell Lymphoma Recruiting
NCT06050694 Feasibility Trial of Glofitamab in a Response Adapted Approach Incorporating Interim FDG… Diffuse Large B Cell Lymphoma (DLBCL) Recruiting
NCT07257055 Phase 2 Study of BTKi-Rituximab Induction Followed by Glofitamab Consolidation in High… Phase 2 Study Recruiting
NCT04889716 CAR-T Followed by Bispecific Antibodies Large B-cell Lymphoma Recruiting
NCT06806033 A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for… B-Cell Non-Hodgkins Lymphoma Recruiting
NCT07003295 Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type… Recurrent Mantle Cell Lymphoma Recruiting
NCT06765317 A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma Diffuse Large B Cell Lymphoma (DLBCL) Recruiting
NCT07326371 Glofitamab Combined With CAR-T Therapy in R/R DLBCL DLBCL - Diffuse Large B Cell Lymphoma Not Yet Recruiting
NCT07387848 Glofitamab as a Bridge to and/or Consolidation Post Autologous Stem Cell Transplant in… Diffuse Large B Cell Lymphoma Refractory Not Yet Recruiting
NCT04980222 A Study to Evaluate the Safety and Efficacy of Glofitamab in Combination With Rituximab… Lymphoma Active, Not Recruiting
NCT05783596 Glofit and Obin in Follicular Lymphoma and Marginal Zone Lymphoma Follicular Lymphoma Active, Not Recruiting
NCT07480850 Efficacy and Safety of Glofitamab Combined With GemOxin the Treatment of Refractory… Refractory Diffuse Large B-Cell Lymphoma (DLBCL) Active, Not Recruiting
NCT07502872 TPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse… Diffuse Large B Cell Lymphoma Not Yet Recruiting
NCT05798156 Rituximab in Combination With Glofitamab and Polatuzumab Vedotin in Patients With… Lymphoma, Large B-Cell, Diffuse Active, Not Recruiting
NCT07453095 Study With Glofitamab in Patients With MCL and Inadequate Response or Relapse Following… Mantle Cell Lymphoma Not Yet Recruiting
NCT07594899 AI-Driven Treatment Strategy vs Pola-R-CHP in Untreated LBCL Large B-Cell Lymphoma (LBCL) Not Yet Recruiting
Sponsors Running Glofitamab Trials
Disease Areas
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