Drug Pipeline

Entrectinib Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
11
Active Studies
3
Recruiting
4
Phase 3
5
Top Sponsors
3
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-28 NCT02568267
Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors…
date change Primary completion pushed: 2026-05-14 -> 2027-06-30
2026-05-28 NCT02568267
Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors…
date change Completion pushed: 2026-05-14 -> 2027-06-30
2026-05-23 NCT04302025
A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages…
Primary endpoint(s) modified
Active Studies by Phase
Phase 3
3
Phase 2/3
1
Phase 2
5
Phase 1/2
1
Phase 1
1
Active Trials
NCT IDTitleConditionStatus
Phase 3
NCT05862285 A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La… Cancer Recruiting
NCT05170204 A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of… Non-Small Cell Lung Cancer Active, Not Recruiting
NCT04603807 A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants… Carcinoma, Non-Small-Cell Lung Active, Not Recruiting
Phase 2/3
NCT03178552 A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments… Non-Small Cell Lung Cancer Active, Not Recruiting
Phase 2
NCT06528691 Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With… High Grade Glioma Recruiting
NCT04302025 A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages… Non-small Cell Lung Cancer Recruiting
NCT03994796 Genetic Testing in Guiding Treatment for Patients With Brain Metastases CDK Gene Mutation Active, Not Recruiting
NCT04589845 Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You… Solid Tumors Active, Not Recruiting
NCT02568267 Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors… Breast Cancer Active, Not Recruiting
Phase 1/2
NCT02650401 Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or… Solid Tumors Active, Not Recruiting
Phase 1
NCT05396859 Entrectinib in Combination With ASTX727 for the Treatment of Relapsed/Refractory TP53… Acute Myeloid Leukemia Active, Not Recruiting
Sponsors Running Entrectinib Trials
Disease Areas
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