Drug Pipeline

Chimeric Antigen Receptor T-Cell Therapy Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
13
Active Studies
11
Recruiting
10
Top Sponsors
1
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-15 NCT07341191
Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma…		 Recruitment opened
Active Studies by Phase
Phase 2
6
Phase 1/2
2
Phase 1
2
Early Phase 1
3
Active Trials
NCT IDTitleConditionStatus
Phase 2
NCT05260957 CAR-T Cell Therapy, Mosunetuzumab and Polatuzumab for Treatment of Refractory/Relapsed… Refractory Non-Hodgkin Lymphoma Recruiting
NCT06834373 Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive… Large B-Cell Lymphoma With IRF4 Rearrangement Recruiting
NCT06104592 Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk… Large B-cell Lymphoma Recruiting
NCT07564453 Full-course Immunotherapy Combined With Chemotherapy in Newly Diagnosed B-cell Acute… B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative Recruiting
NCT06784726 Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T Recurrent Diffuse Large B-Cell Lymphoma Recruiting
NCT07341191 Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma… Mantle Cell Lymphoma Recruiting
Phase 1/2
NCT06768905 IOMAB-CAR-T Followed by CAR-T Cell Therapy in R/R DLBCL Non Hodgkin Lymphoma Recruiting
NCT03277729 A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T… Recurrent B-Cell Non-Hodgkin Lymphoma Active, Not Recruiting
Phase 1
NCT05003895 GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Solid Tumor Malignancies Hepatocellular Carcinoma Recruiting
NCT03696030 HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases Malignant Neoplasm Active, Not Recruiting
Early Phase 1
NCT07344818 An Open and Dose-escalation Early Clinical Study of CD19 and CD20 CAR-T Cell Therapy for… R/R Aggressive B-cell Lymphoma Recruiting
NCT05800405 Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of… Recurrent Diffuse Large B-Cell Lymphoma Recruiting
NCT05587543 Clinical Study on the EBV CAR-T /TCR-T Cells in the Treatment of Nasopharyngeal Carcinoma Nasopharyngeal Carcinoma Recruiting
Sponsors Running Chimeric Antigen Receptor T-Cell Therapy Trials
City of Hope Medical Center (2) Fred Hutchinson Cancer Center (1) National Cancer Institute (NCI) (1) Lazaros Lekakis (1) Fudan University (1) H. Lee Moffitt Cancer Center and Research Institute (1) University of Texas Southwestern Medical Center (1) University of Washington (1) Mayo Clinic (1) Canadian Cancer Trials Group (1)
Disease Areas
Non-Hodgkin Lymphoma (6) DLBCL (4) Follicular Lymphoma (3) Leukemia (2) Mantle Cell Lymphoma (2) Chronic Lymphocytic Leukemia (CLL) (1) Breast Cancer (1) HER2-Positive Breast Cancer (1) Liver Cancer (1) Acute Lymphoblastic Leukemia (ALL) (1)
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