| Detected | Trial | Change |
|---|---|---|
| 2026-05-28 | NCT07100080 Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated… |
Enrollment reduced: 596 -> 500 participants |
| 2026-05-28 | NCT07100080 Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated… |
date change Primary completion pushed: 2028-09-15 -> 2028-12-15 |
| 2026-05-28 | NCT07100080 Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated… |
date change Completion moved earlier: 2031-05-15 -> 2030-11-15 |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-11 | NCT07640789 A Study Comparing BL-B01D1 in Combination With Osimertinib Versus Osimertinib Alone in… | Phase 3 | Not Yet Recruiting |
| 2026-06-11 | NCT07641855 A Study of BL-B01D1 Combination Therapy in Patients With Metastatic Castration-resistant… | Phase 2/3 | Not Yet Recruiting |
| 2026-06-11 | NCT07642024 A Study of BL-B01D1 in Combination With Osimertinib as Perioperative Therapy in Patients… | Phase 2/3 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06838273 | A Study of BL-B01D1 in Combination With Osimertinib Versus Osimertinib as First-Line… | Non-small Cell Lung Cancer | Recruiting |
| NCT06857175 | A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With… | Urothelial Carcinoma | Recruiting |
| NCT06994195 | A Study Comparing BL-B01D1 With the Investigator's Choice of Chemotherapy in Patients… | Epithelial Ovarian Cancer | Recruiting |
| NCT06118333 | A Study Comparing BL-B01D1 With Physician's Choice of Chemotherapy in Patients With… | Nasopharyngeal Carcinoma | Active, Not Recruiting |
| NCT06304974 | A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With… | Esophageal Squamous Cell Carcinoma | Active, Not Recruiting |
| NCT06343948 | A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With… | HR+HER2- Breast Cancer | Active, Not Recruiting |
| NCT06382116 | A Study Comparing BL-B01D1 With Platinum Based Chemotherapy in Patients With Locally… | Non-small Cell Lung Cancer | Active, Not Recruiting |
| NCT06382129 | A Study Comparing BL-B01D1 With Docetaxel in Patients With Unresectable Locally Advanced… | Non-small Cell Lung Cancer | Active, Not Recruiting |
| NCT06500026 | A Study Comparing BL-B01D1 With Topotecan in Patients With Recurrent Small Cell Lung… | Small Cell Lung Cancer | Active, Not Recruiting |
| NCT06382142 | A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With… | Triple-Negative Breast Cancer | Active, Not Recruiting |
| NCT07502300 | A Study Comparing BL-B01D1 Combined With Tislelizumab Versus Platinum-containing… | Extensive-stage Small-cell Lung Cancer | Not Yet Recruiting |
| NCT07582315 | A Study Comparing BL-B01D1 With Treatment of Physician's Choice in Patients With Locally… | Biliary Tract Cancer | Not Yet Recruiting |
| NCT07640789 | A Study Comparing BL-B01D1 in Combination With Osimertinib Versus Osimertinib Alone in… | Non-small Cell Lung Cancer Stage III | Not Yet Recruiting |
| Phase 2/3 | |||
| NCT07100080 | Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated… | Non-Small Cell Lung Cancer | Recruiting |
| NCT07106762 | Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic… | Urothelial Cancer | Recruiting |
| NCT06926868 | A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously… | Breast Neoplasms | Recruiting |
| NCT07554456 | A Study of BL-B01D1 in Combination With Tislelizumab ±5-Fluorouracil Versus… | Esophageal Squamous Cell Carcinoma | Not Yet Recruiting |
| NCT07641855 | A Study of BL-B01D1 Combination Therapy in Patients With Metastatic Castration-resistant… | Castration-resistant Prostate Cancer | Not Yet Recruiting |
| NCT07642024 | A Study of BL-B01D1 in Combination With Osimertinib as Perioperative Therapy in Patients… | Non-small Cell Lung Cancer | Not Yet Recruiting |
| Phase 2 | |||
| NCT07054567 | A Study of BL-B01D1 + Pembrolizumab ± Bevacizumab in Patients With Recurrent or… | Cervical Cancer | Recruiting |
| NCT06475300 | A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or… | Non-small Cell Lung Cancer | Recruiting |
| NCT06986785 | A Study of BL-B01D1 Monotherapy, BL-B01D1 in Combination With Lenvatinib, BL-B01D1 in… | Advanced Hepatocellular Carcinoma | Recruiting |
| NCT06787664 | A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Chordoma | Chordoma | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT06618287 | A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of… | Lung Cancer | Recruiting |
| NCT07307053 | Rare Tumor Focused Platform Study of Innovative Therapies and Technologies (PLATFORM2) | Rare Malignant Neoplasm | Not Yet Recruiting |