Drug Pipeline

Amivantamab Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
28
Active Studies
12
Recruiting
6
Phase 3
10
Top Sponsors
4
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT06532032
A Study of Combination Therapy With Amivantamab and Docetaxel in Participants With…
Trial completed
2026-06-06 NCT06750094
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in…
Trial sites expanded: 241 -> 247 locations
2026-06-06 NCT07276399
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC…
Trial sites expanded: 177 -> 186 locations
2026-06-03 NCT05663866
Premedication to Reduce Amivantamab Associated Infusion Related Reactions
date change Completion pushed: 2026-07-30 -> 2027-03-31
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-05-14 NCT07586202 A Study of Neoadjuvant Amivantamab With Either Lazertinib or Chemotherapy in Participants… Phase 2 Not Yet Recruiting
Active Studies by Phase
Phase 3
6
Phase 2
12
Phase 1/2
7
Phase 1
3
Active Trials — top 25 of 28
NCT IDTitleConditionStatus
Phase 3
NCT06662786 A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI… Colorectal Neoplasms Recruiting
NCT06750094 A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in… Colorectal Neoplasms Recruiting
NCT07276399 A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC… Squamous Cell Carcinoma of Head and Neck Recruiting
NCT04487080 A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally… Carcinoma, Non-Small-Cell Lung Active, Not Recruiting
NCT04538664 A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With… Carcinoma, Non-Small-Cell Lung Active, Not Recruiting
NCT04988295 A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy… Carcinoma, Non-Small-Cell Lung Active, Not Recruiting
Phase 2
NCT07392658 Phase II Trial of Amivantamab Plus Monochemotherapy in Platinum Unfit NSCLC Patients With… Metastatic NSCLC - Non-Small Cell Lung Cancer Recruiting
NCT05845450 Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer… Colorectal Cancer Recruiting
NCT06116682 Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of… Lung Non-Small Cell Carcinoma Recruiting
NCT05498428 A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including… Carcinoma, Non-small-Cell Lung Recruiting
NCT06667076 A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With… Carcinoma, Non-Small-Cell Lung Recruiting
NCT05601973 Amivantamab, Lazertinib and Bevacizumab in Patients With EGFR-mutant Advanced Non-small… Non Small Cell Lung Cancer Active, Not Recruiting
NCT05117931 A Study of Amivantamab in People With Esophagogastric Cancer Esophagogastric Cancer Active, Not Recruiting
NCT05801029 A Study to Investigate Safety and Efficacy of Osimertinib and Amivantamab in Participants… Non-Small Cell Lung Cancer (NSCLC) Active, Not Recruiting
NCT05074940 Amivantamab in Adenoid Cystic Carcinoma Salivary Gland Cancer Active, Not Recruiting
NCT06120140 Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor… Carcinoma, Non-Small-Cell Lung Active, Not Recruiting
NCT05663866 Premedication to Reduce Amivantamab Associated Infusion Related Reactions Carcinoma, Non-Small-Cell Lung Active, Not Recruiting
NCT07586202 A Study of Neoadjuvant Amivantamab With Either Lazertinib or Chemotherapy in Participants… Carcinoma, Non-Small-Cell Lung Not Yet Recruiting
Phase 1/2
NCT05379595 A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in… Advanced or Metastatic Colorectal Cancer Recruiting
NCT06385080 A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants… Squamous Cell Carcinoma of Head and Neck Recruiting
NCT07227025 A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic… Carcinoma, Non-Small-Cell Lung Recruiting
NCT05845671 Amivantamab With Tyrosine Kinase Inhibitors (TKI) for Advanced NSCLC With ALK, ROS1, or… Lung Cancer Active, Not Recruiting
NCT06083857 PhI/II Study of Amivantamab and Tepotinib Combo in MET-altered Non-small Cell Lung Cancer Non-small Cell Lung Cancer Active, Not Recruiting
NCT05488314 A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic… Carcinoma, Non-Small-Cell Lung Active, Not Recruiting
NCT05908734 A Study of Combination Therapy With Amivantamab and Cetrelimab in Participants With… Carcinoma, Non-Small-Cell Lung Active, Not Recruiting
Sponsors Running Amivantamab Trials
Disease Areas
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