| Detected | Trial | Change |
|---|---|---|
| 2026-06-09 | NCT06819891 A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart… |
Trial sites expanded: 173 -> 178 locations |
| 2026-06-02 | NCT07137598 A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to… |
Trial sites expanded: 46 -> 51 locations |
| 2026-05-23 | NCT07158242 A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121)… |
Trial sites expanded: 9 -> 12 locations |
| 2026-05-16 | NCT07298421 A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for… |
Recruitment opened |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-02 | NCT07620392 An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants… | Phase 2 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT07298421 | A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for… | Moderately to Severely Active Crohns Disease | Recruiting |
| NCT07158242 | A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121)… | Moderately to Severely Active Ulcerative Colitis | Recruiting |
| NCT06588855 | A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also… | Moderately to Severely Active Ulcerative Colitis | Recruiting |
| NCT06819878 | A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With… | Moderately to Severely Active Crohns Disease | Recruiting |
| NCT06819891 | A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart… | Moderately to Severely Active Crohns Disease | Recruiting |
| NCT06589986 | A Study to Assess the Efficacy and Safety of Afimkibart (Also Known as RO7790121) for… | Moderately to Severely Active Ulcerative Colitis | Active, Not Recruiting |
| Phase 2 | |||
| NCT07137598 | A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to… | Rheumatoid Arthritis | Recruiting |
| NCT07223697 | A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121)… | Atopic Dermatitis | Recruiting |
| NCT05910528 | Afimkibart (RO7790121) for the Treatment of Moderate to Severe Active Crohn's Disease | Crohns Disease | Active, Not Recruiting |
| NCT06863961 | A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With… | Atopic Dermatitis | Active, Not Recruiting |
| NCT07620392 | An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants… | Rheumatoid Arthritis | Not Yet Recruiting |
| Phase 1 | |||
| NCT06903065 | A Study to Assess the Safety, Pharmacokinetics, and Activity of RO7790121 in Participants… | MASH | Active, Not Recruiting |