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A Clinical Study of Sotatercept (MK-7962) in People With Combined Postcapillary and Precapillary Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (MK-7962-041)

Name: A Clinical Study of Sotatercept (MK-7962) in People With Combined Postcapillary and Precapillary Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (MK-7962-041) — clinical trial record (NCT07839585)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: CHORUS

StatusNot Yet Recruiting

PhasePhase 3

SponsorMerck Sharp & Dohme LLC

Started2026-11-26

View on ClinicalTrials.gov ↗

Merck (MSD)

401 trials monitored

See 24 trials at risk

Hypertension

1,786 trials monitored

See 77 trials at risk

Researchers are looking for other ways to treat people with combined postcapillary and precapillary pulmonary hypertension (CpcPH). This trial focuses on CpcPH that is related to heart failure with preserved ejection fraction (HFpEF). The goal of the study is to learn if participants who receive sotatercept live longer without their CpcPH-HFpEF getting worse than those who receive placebo.

Trial Details

NCT Number	NCT07839585
Lead Sponsor	Merck Sharp & Dohme LLC
Conditions	Pulmonary Hypertension
Enrollment	352 participants
Start Date	2026-11-26
Primary Completion	2030-01-08 (estimated)
Study Completion	2030-06-14 (estimated)
Updated on ClinicalTrials.gov	2026-09-24