Clinical Trial

Platform Trial in Stage 1 Diabetes: Comparing Golimumab vs Placebo

Not Yet Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to learn if golimumab is effective at preventing progression to Stage 2 diabetes in participants with presymptomatic Type 1 Diabetes. The expected duration of this study is approximately 6 years. Participants will: * Take golimumab or placebo injections monthly for the duration of the study or until they are diagnosed with either stage 2 or stage 3 Type 1 Diabetes * Visit a study clinic every 6 months for Oral Glucose Tolerance Tests (OGTTs) and other tests until the end of the study
Trial Details
NCT Number NCT07683026
Lead Sponsor National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions Type 1 Diabetes (T1D)
Enrollment 255 participants
Start Date 2026-08-08
Primary Completion 2032-09-01 (estimated)
Study Completion 2032-09-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-06