Precise Eating Time to Improve Glycemic Control and Cardiometabolic Health in Prediabetes and Diabetes

The objective of this study is to investigate the impact of hypocaloric time-restricted eating (TRE) at different day times (early versus late TRE) on glucose metabolism and other cardiometabolic parameters in individuals with overweight and with normal, or impaired glucose metabolism (prediabetes and type 2 diabetes). In addition, the study aims to elucidate the molecular mechanisms underlying these effects.

NCT Number	NCT07171281
Lead Sponsor	German Institute of Human Nutrition Collaborators: Technische Universität Dresden, University of Surrey, UK, University of Geneva, Switzerland, Technische Universität München, Germany, German Center for Diabetes Research, University of Rovira i Virgili, Spain
Conditions	Prediabetes, Type 2 Diabetes, Obesity & Overweight
Enrollment	30 participants
Start Date	2025-09-19
Primary Completion	2027-12-31 (estimated)
Study Completion	2028-02-28 (estimated)
Updated on ClinicalTrials.gov	2025-09-12