Clinical Trial

Cardiac Amyloid Deposits and Heart Dysfunction in Alzheimer's Disease

Recruiting
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Summary
This study seeks to explore the possible common pathogenesis of both cardiac amyloidosis and Alzheimer's disease, which can both be associated with amyloid deposits. Using Positron Emission Tomography (PET) scans with amyloid tracers - a conventional tool for non-invasively imaging amyloid deposits in Alzheimer's disease - the research will extend this imaging methodology to the heart. The study will conduct additional PET/MRI scans of the heart in patients undergoing amyloid tracer PET scans for Alzheimer's evaluations. Each participant will also undergo an echocardiogram and a clinical examination of dementia. This could potentially enhance diagnostic practices in both cardiac amyloidosis and Alzheimer's disease.
Trial Details
NCT Number NCT07154394
Lead Sponsor University Hospital, Essen
Conditions Dementia, Alzheimer Type, Mild Cognitive Impairment, Cardiac Amyloidosis
Enrollment 15 participants
Start Date 2022-08-15
Primary Completion 2023-08-14 (estimated)
Study Completion 2025-09-14 (estimated)
Updated on ClinicalTrials.gov 2025-09-04