Clinical Trial

HEARTS Trial for Thoracic Cancers

Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to compare a new way of using magnetic resonance-guided adaptive radiation therapy (MRgART) to the standard of care linear accelerator (LINAC) radiation treatment in people with cancer in the thoracic region near the heart. The main question it aims to answer is whether MRgART affects the heart differently than LINAC. Participants will: * Receive radiation therapy * Undergo MRIs and bloodwork * Complete quality of life questionnaires
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2025-08-12; most recent amendment 2026-03-09.
Status change: Not Yet Recruiting → Recruiting 2025-08-25
Trial Details
NCT Number NCT07132918
Lead Sponsor University of Wisconsin, Madison
Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
Conditions Non-Small Cell Lung Cancer (Stage III), Esophageal Cancer Stage I-III, Esophagogastric Cancer Stage I-III, Thymoma and Thymic Carcinoma Stage II-III, Other Cancers in the Thoracic Region
Enrollment 60 participants
Start Date 2025-10-08
Primary Completion 2029-03 (estimated)
Study Completion 2029-03 (estimated)
Updated on ClinicalTrials.gov 2026-03-11