Accelerated TMS for Perinatal Depression

We are studying a treatment for depression called accelerated Transcranial Magnetic Stimulation (TMS) among pregnant and postpartum individuals. TMS is a focal, non-invasive form of brain stimulation that is cleared by the Food and Drug Administration for depression. Typically, traditional TMS involves daily treatments for 6-8 weeks. In this study, we will offer an accelerated form of TMS that involves multiple daily treatments for 5 days.

NCT Number	NCT06968390
Lead Sponsor	Brigham and Women's Hospital
Conditions	Perinatal Depression, Post Partum Depression, Major Depressive Disorder
Enrollment	24 participants
Start Date	2025-08-05
Primary Completion	2026-11-30 (estimated)
Study Completion	2027-01-01 (estimated)
Updated on ClinicalTrials.gov	2025-09-09