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Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation

Study acronym: SEMINAL-AF
StatusRecruiting
PhasePhase 3
Started
View on ClinicalTrials.gov ↗

Record History

  1. Re-verified, no change to tracked fieldsv7
  2. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Jun 2025 to Apr 14, 2025
    • Site details revised at 2 of 2 sites
    v6
  3. Start date: Mar 2025 to Jun 2025v5
  4. Start date: Jan 2025 to Mar 2025v4
  5. Secondary endpoints: details revised at 1 of 16 entriesv3
  6. Start date: Jul 2024 to Jan 2025v2
  7. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
University of Chicago
307 trials monitored
See 12 trials at risk
Heart Disease
8,786 trials monitored
See 412 trials at risk
Obesity
3,874 trials monitored
See 152 trials at risk
Atrial Fibrillation
1,182 trials monitored
See 50 trials at risk
The goal of the study is to learn how a weight loss medication called semaglutide, which is used to treat obesity, in addition to standard AF treatment might affect AF, atrial fibrillation severity, and whether it changes the risk of atrial fibrillation recurring after standard AF treatments.
Trial Details
NCT Number NCT06499857
Lead Sponsor University of Chicago
Conditions
(from sponsor)		 Overweight or Obesity, Atrial Fibrillation
Related terms Atrial Fibrillation, Obesity, Overweight
Enrollment 200 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov