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NCT06399757 · ClinicalTrials.gov record · last posted 2026-08-13

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

Name: A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors — clinical trial record (NCT06399757)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusActive, Not Recruiting

PhasePhase 1/2

SponsorApollo Therapeutics Ltd

Started2024-06-18

View on ClinicalTrials.gov ↗

from the ClinicalTrials.gov record

This is an open-label, Phase 1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced or metastatic solid tumors with particular focus on Colorectal carcinoma (CRC).

Protocol amendment history 1 change detected by DataLookout

2026-08-14

Enrollment closed, study ongoing

Trial Details

NCT Number	NCT06399757
Lead Sponsor	Apollo Therapeutics Ltd
Conditions	Colorectal Cancer, Cholangiocarcinoma, Appendiceal Adenocarcinoma, Pancreatic Adenocarcinoma, Gastric Adenocarcinoma, Endometrial Adenocarcinoma, Triple Negative Breast Cancer, Ovarian Cancer +1 more
Enrollment	100 participants
Start Date	2024-06-18
Primary Completion	2027-04 (estimated)
Study Completion	2027-05 (estimated)
Updated on ClinicalTrials.gov	2026-08-13