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Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation

Study acronym: ATRACTion
StatusCompleted
PhaseNot specified
Started
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Record History

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  1. Trial completed Show 5 more changesShow less
    • Final enrollment: 325 participants (planned 500)
    • Study completion date changed from estimate of Jun 2026 to Oct 21, 2025
    • Eligibility criteria expanded, about 7 words
    • Secondary endpoints: details revised at 1 of 3 entries
    • Site details revised
  2. Trial status: Not Yet Recruiting to Recruitingv3 Show 4 more changesShow less
    • Study sites: 0 to 1
    • Primary completion date changed from estimate of Dec 2024 to May 14, 2025
    • Study completion date: Dec 2024 to Jun 2026
    • Start date changed from estimate of Jun 2021 to Sep 7, 2021
  3. Secondary endpoints revised (3)
    • Study description revised
    • Eligibility criteria expanded, about 2 words
    v2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The main objective of this study is to generate diagnosis and therapeutic-decision tools through the identification of molecular causes of PIDs with autoimmunity/inflammation and the variability in disease outcome at the transcriptional level using a combination of omics signatures (transcriptomics, epigenomics, proteomics, metagenomics, metabolomics and lipidomics).
Trial Details
NCT Number NCT04902807
Lead Sponsor Institut National de la Santé Et de la Recherche Médicale, France
Conditions
(from sponsor)		 Autoimmune Lymphoproliferative Syndrome, Autoimmune Cytopenia, Autoimmune Diseases, Autoimmune Anemia, Autoimmune Thrombocytopenia, Autoimmune Hepatitis, Autoimmune Diabetes, Autoimmune Rheumatologic Disease +12 more
Related terms Arthritis, Juvenile, Autoimmune Diseases, Autoimmune enteropathy, Autoimmune Lymphoproliferative Syndrome, Diabetes Mellitus, Type 1, Hepatitis, Autoimmune, Lupus Erythematosus, Systemic, Lymphohistiocytosis, Hemophagocytic, Polyendocrinopathies, Autoimmune, Primary Immunodeficiency Diseases, Purpura, Thrombocytopenic, Idiopathic
Enrollment 325 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov