Sponsor Pipeline

Merck KGaA (Germany) Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
27
Active Trials
12
Recruiting
6
Phase 3
10
Disease Areas
12
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT07340827
A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG…
Enrollment reduced: 333 -> 266 participants
2026-06-12 NCT07340827
A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG…
date change Primary completion moved earlier: 2028-10-31 -> 2028-07-05
2026-06-12 NCT07340827
A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG…
date change Completion moved earlier: 2029-06-30 -> 2028-07-05
2026-06-04 NCT06433219
Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian…
date change Primary completion pushed: 2025-09-29 -> 2026-06-14
2026-05-29 NCT05396833
Study of Tuvusertib (M1774) in Combination With DNA Damage Response Inhibitor or Immune…
date change Primary completion pushed: 2026-04-10 -> 2027-01-14
2026-05-29 NCT05396833
Study of Tuvusertib (M1774) in Combination With DNA Damage Response Inhibitor or Immune…
date change Completion pushed: 2026-04-10 -> 2027-01-14
2026-05-29 NCT06710132
Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE…
overall status: "Recruiting" → "Active Not Recruiting"
2026-05-29 NCT05882734
Tuvusertib (M1774) in Combination With Cemiplimab in Participants With Non-Squamous NSCLC…
date change Primary completion pushed: 2026-03-30 -> 2026-09-30
2026-05-29 NCT05882734
Tuvusertib (M1774) in Combination With Cemiplimab in Participants With Non-Squamous NSCLC…
date change Completion pushed: 2026-03-30 -> 2026-09-30
2026-05-23 NCT06463587
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in…
Trial sites expanded: 133 -> 138 locations
2026-05-23 NCT06463587
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in…
date change Primary completion pushed: 2028-05-19 -> 2028-08-23
2026-05-23 NCT06463587
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in…
date change Completion pushed: 2030-08-19 -> 2030-11-12
Active Trials by Phase
Phase 3
6
Phase 2
6
Phase 1/2
2
Phase 1
10
Not specified
3
Active Trials — top 25 of 27
NCT IDTitleConditionStatus
Phase 3
NCT07332481 A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or… Systemic Lupus Erythematosus (SLE) Recruiting
NCT07549412 A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to… Metastatic Colorectal Cancer Recruiting
NCT07355218 A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or… Systematic Lupus Erythematosus Recruiting
NCT06463587 Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in… Generalized Myasthenia Gravis Recruiting
NCT07340827 A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG… Infertility Recruiting
NCT03815643 Avelumab Program Rollover Study Solid Tumors Active, Not Recruiting
Phase 2
NCT07499362 Study of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor (TGCT)… Tenosynovial Giant Cell Tumor Recruiting
NCT03940703 A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC… Non-small Cell Lung Cancer Active, Not Recruiting
NCT02864992 Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION) Advanced (Stage IIIB/IV) Non-small Cell Lung Cancer (NSCLC) With MET Exon 14 (METex14) Skipping Alterations or MET Amplification Active, Not Recruiting
NCT05540327 The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE) Systemic Lupus Erythematosus Active, Not Recruiting
NCT05327530 A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in… Locally Advanced or Metastatic Urothelial Carcinoma Active, Not Recruiting
NCT06433219 Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian… Ovarian Cancer Active, Not Recruiting
Phase 1/2
NCT05882734 Tuvusertib (M1774) in Combination With Cemiplimab in Participants With Non-Squamous NSCLC… Non-Small Cell Lung Cancer Active, Not Recruiting
NCT06710132 Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE… Solid Tumors Active, Not Recruiting
Phase 1
NCT06577337 Phase 1 Single Ascending Doses (SAD) of M5542 in Healthy Participants Healthy Recruiting
NCT06641908 Anti-GD2 ADC M3554 in Advanced Solid Tumors Advanced Solid Tumor Recruiting
NCT07166601 M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in… Advanced Solid Tumor Recruiting
NCT05464030 Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01) Colorectal Cancer Recruiting
NCT07360314 Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors Advanced Solid Tumors Recruiting
NCT06421935 M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501) Advanced Solid Tumor Active, Not Recruiting
NCT05081180 Study of Avelumab in Combination With Lenvatinib for Children With Primary CNS Tumors Central Nervous System Tumors Active, Not Recruiting
NCT04170153 Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid… Metastatic or Locally Advanced Unresectable Solid Tumors Active, Not Recruiting
NCT06806046 Anti-CEACAM5 ADC Precemtabart Tocentecan (M9140) in Chinese Participants With Solid Tumors Solid Tumors Active, Not Recruiting
NCT05396833 Study of Tuvusertib (M1774) in Combination With DNA Damage Response Inhibitor or Immune… Metastatic or Locally Advanced Unresectable Solid Tumors Active, Not Recruiting
Not specified
NCT05376891 Met Non Small Cell Cancer Registry (MOMENT) Cancer Recruiting
View all 27 active Merck KGaA (Germany) trials with filters →
Disease Areas
Get alerts when Merck KGaA (Germany)'s trials change
Status changes, date slips, and new filings — detected daily, delivered to your inbox.
Start monitoring free