Sponsor pipeline

National Institute on Drug Abuse (NIDA) clinical trial pipeline

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20 active trials 12 recruiting 1 Phase 3 1 disease areas 2 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-11

What changed in the last 30 days

2 trials changed in the last 30 days: 0 stopped, 2 with notable changes, 0 with minor changes only.

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

Active trials by phase

Early Phase 1
2
Phase 1
5
Phase 2
2
Phase 3
1
Not charted: 10 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials

NCT IDTitleConditionStatusUpdated
Phase 3
NCT06233799 Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder Methamphetamine-dependence Active, Not Recruiting 2026-07-13
Phase 2
NCT07468552 Trial of Tirzepatide for the Treatment of Cannabis Use Disorder Cannabis Use Disorder Not Yet Recruiting 2026-09-21
NCT06015893 Semaglutide Therapy for Alcohol Reduction (STAR) Addiction Active, Not Recruiting 2026-09-02
Phase 1
NCT06860607 Environment and Alcohol: A Pilot Study Alcohol Use Disorder Recruiting 2026-10-09
NCT05807139 Spironolactone in Alcohol Use Disorder (SAUD) Alcohol Use Disorder Recruiting 2026-09-21
NCT06868914 Phase I Trial of High-Density Theta Burst Stimulation (hdTBS) Healthy Volunteers Not Yet Recruiting 2026-10-09
NCT07204171 Phase 1 Study of Oral MG001 Safety and Tolerability in Healthy Subjects Not Yet Recruiting 2026-06-16
NCT06808932 VK4-116 Phase I Study With Food-Effect Opioid Dependence Not Yet Recruiting 2026-04-09
Early Phase 1
NCT06561828 Developing Transcranial Neuromodulation Protocols for Learning and Decision-Making Normal Physiology Recruiting 2026-10-09
NCT07099092 Causal Mechanisms of Odor-Guided Behavior in Humans Normal Physiology Not Yet Recruiting 2026-10-09
Not applicable
NCT03394066 Mechanism of Non-invasive Magnetic Stimulation Healthy Volunteers Recruiting 2026-10-08
NCT01036581 Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging Drug Abuse Recruiting 2026-10-02
NCT05538910 Defining Neurobiological Links Between Substance Use and Mental Illness Major Depressive Disorder Recruiting 2026-09-11
NCT05630781 Orexin s Role in the Neurobiology of Substance Use Disorder Nicotine Dependence Recruiting 2026-09-11
Not specified
NCT06676059 SMART-r: Substance Monitoring and Active Relapse Tracking Repository Alcoholism Recruiting 2026-10-09
NCT07637669 Olfactory Function and Model-Based Behavior in People Living With HIV and SUD HIV Recruiting 2026-10-09
NCT03745339 Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder Opioid-Related Disorders Recruiting 2026-10-02
NCT05707806 Development and Validation of Learning and Decision-Making Tasks Normal Physiology Recruiting 2026-09-28
NCT06552741 Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP Substance Use Disorder Recruiting 2026-08-24
NCT06995885 Development of an Interview-Informed Timeline Follow-Back (TLFB) for Opioid Use in the… Substance Use Disorders (SUDs) Enrolling by Invitation 2026-10-09

Disease areas by active trials

Depression (1)

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