Sponsor pipeline

Loxo Oncology, Inc. clinical trial pipeline

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7 active trials 2 recruiting 6 Phase 3 4 disease areas

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-16

Active trials by phase

Phase 2
1
Phase 3
6

Active trials

NCT IDTitleConditionStatusUpdated
Phase 3
NCT05254743 A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic… Chronic Lymphocytic Leukemia Recruiting 2026-08-17
NCT04662255 Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With… Lymphoma, Mantle-Cell Active, Not Recruiting 2026-05-15
NCT04666038 Study of LOXO-305 (Pirtobrutinib) Versus Investigator's Choice (Idelalisib Plus Rituximab… Chronic Lymphocytic Leukemia Active, Not Recruiting 2026-04-24
NCT04211337 A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid… Medullary Thyroid Cancer Active, Not Recruiting 2026-03-19
NCT04965493 A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax… Chronic Lymphocytic Leukemia Active, Not Recruiting 2026-01-29
NCT05023980 A Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated… Chronic Lymphocytic Leukemia Active, Not Recruiting 2026-01-22
Phase 2
NCT06588478 A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed… Chronic Lymphocytic Leukemia Recruiting 2026-05-19

Disease areas by active trials

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