Sponsor Pipeline

Blueprint Medicines Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
8
Active Trials
6
Recruiting
1
Phase 3
4
Disease Areas
6
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-13 NCT07143669
Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations		 Primary endpoint(s) modified
2026-08-13 NCT07143669
Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations		 Enrollment increased: 450 -> 750 participants
2026-08-13 NCT07143669
Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations		 Trial arms changed: 3 -> 4
2026-08-13 NCT07143669
Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations		 Trial sites expanded: 19 -> 22 locations
2026-08-05 NCT04910685
(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With…		 Trial sites expanded: 71 -> 75 locations
2026-07-23 NCT06931405
Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria…		 overall status: Recruiting → Active, Not Recruiting
Active Trials by Phase
Phase 4
1
Phase 2/3
1
Phase 2
2
Phase 1/2
1
Not specified
3
Active Trials
NCT IDTitleConditionStatus
Phase 4
NCT06748001 Avapritinib Rollover Study Mastocytosis, Systemic Recruiting
Phase 2/3
NCT04910685 (HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With… Indolent Systemic Mastocytosis Recruiting
Phase 2
NCT03731260 (PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT… Indolent Systemic Mastocytosis Active, Not Recruiting
NCT06931405 Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria… Chronic Inducible Urticaria Active, Not Recruiting
Phase 1/2
NCT07629960 A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS… Advanced Solid Tumor Recruiting
Not specified
NCT07255638 A Non-Interventional Study in Participants With Indolent Systemic Mastocytosis (ISM) in… Indolent Systemic Mastocytosis Recruiting
NCT07264959 An Observational Study in Participants With Indolent Systemic Mastocytosis (ISM) Indolent Systemic Mastocytosis Recruiting
NCT07143669 Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations Clonal Mast Cell Disease Recruiting
Disease Areas
Non-Small Cell Lung Cancer (NSCLC) (1) Lung Cancer (1) Colorectal Cancer (1) Pancreatic Cancer (1)
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