Drug Pipeline

Zanidatamab Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
15
Active Studies
11
Recruiting
4
Phase 3
10
Top Sponsors
4
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-10 NCT06695845
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
Trial sites expanded: 21 -> 28 locations
2026-06-04 NCT04164199
Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With…
Trial completed
2026-06-04 NCT04164199
Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With…
date change Primary completion moved earlier: 2026-07 -> 2026-05-23
2026-06-04 NCT04164199
Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With…
date change Completion moved earlier: 2026-07 -> 2026-05-23
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-08 NCT07631871 An Exploratory Study of Zanidatamab in HER2-positive Advanced Tumor After at Least One… Phase 2 Not Yet Recruiting
Active Studies by Phase
Phase 3
4
Phase 2
9
Phase 1/2
2
Active Trials
NCT IDTitleConditionStatus
Phase 3
NCT06435429 A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in… Metastatic HER2-positive Breast Cancer Recruiting
NCT06282575 Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care… Biliary Tract Cancer Recruiting
NCT05615818 Personalized Medicine for Advanced Biliary Cancer Patients Biliary Tract Neoplasms Recruiting
NCT05152147 A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in… Gastric Neoplasms Active, Not Recruiting
Phase 2
NCT07176312 Zanidatamab in Combination With Pembrolizumab and Chemotherapy in HER2 and PD-L1 Positive… Gastroesophageal Adenocarcinoma Recruiting
NCT07405476 Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in… Colon Carcinoma Recruiting
NCT07102381 A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in… HER2-positive Breast Cancer Recruiting
NCT01042379 I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer Breast Neoplasms Recruiting
NCT05035836 A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients… Breast Cancer Recruiting
NCT06043427 Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal… Gastroesophageal Adenocarcinoma Recruiting
NCT06695845 A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors Breast Cancer Recruiting
NCT07290985 AACR Adaptive Biomarker-Driven Organ Preservation Trial in Gastroesophageal… Gastroesophageal Adenocarcinoma Not Yet Recruiting
NCT07631871 An Exploratory Study of Zanidatamab in HER2-positive Advanced Tumor After at Least One… Neoplasms Not Yet Recruiting
Phase 1/2
NCT06324357 Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in… Metastatic Breast Cancer Recruiting
NCT07494448 Phase Ib/II Study of Zanidatamab Plus Tucatinib and Chemotherapy in HER2-Positive… HER 2 Positive Advanced Breast Cancer Not Yet Recruiting
Sponsors Running Zanidatamab Trials
Disease Areas
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