Drug Pipeline

Venetoclax Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
269
Active Studies
139
Recruiting
42
Phase 3
10
Top Sponsors
58
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT06917911
Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment…
Trial sites expanded: 7 -> 14 locations
2026-06-12 NCT04847453
Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or…
date change Primary completion pushed: 2026-06-30 -> 2028-06-30
2026-06-12 NCT04847453
Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or…
date change Completion pushed: 2026-06-30 -> 2028-06-30
2026-06-12 NCT03041688
Testing a New Chemotherapy Drug, KRT-232 (AMG-232) in Combination With Decitabine and…
date change Primary completion pushed: 2026-06-30 -> 2027-06-30
2026-06-12 NCT03041688
Testing a New Chemotherapy Drug, KRT-232 (AMG-232) in Combination With Decitabine and…
date change Completion pushed: 2026-06-30 -> 2027-06-30
2026-06-10 NCT07490288
Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML
Recruitment opened
2026-06-10 NCT07490288
Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML
Primary endpoint(s) modified
2026-06-10 NCT07490288
Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML
Enrollment reduced: 30 -> 27 participants
2026-06-09 NCT07200102
Selinexor Maintenance Post CAR-T Cell Therapy for Multiple Myeloma
Primary endpoint(s) modified
2026-06-06 NCT05053659
Loncastuximab Tesirine and Venetoclax for Relapsed/ Refractory Non-Hodgkin Lymphoma
date change Primary completion pushed: 2026-06 -> 2026-11
2026-06-06 NCT05053659
Loncastuximab Tesirine and Venetoclax for Relapsed/ Refractory Non-Hodgkin Lymphoma
date change Completion pushed: 2026-06 -> 2026-11
2026-06-06 NCT04550442
Venetoclax and Azacitidine for the Treatment of Relapsed or Refractory High-Risk…
Trial terminated
2026-06-06 NCT04550442
Venetoclax and Azacitidine for the Treatment of Relapsed or Refractory High-Risk…
critical why stopped: null → "\\<75% participation"
2026-06-06 NCT04550442
Venetoclax and Azacitidine for the Treatment of Relapsed or Refractory High-Risk…
date change Primary completion pushed: 2026-03-31 -> 2026-05-29
2026-06-06 NCT04550442
Venetoclax and Azacitidine for the Treatment of Relapsed or Refractory High-Risk…
date change Completion pushed: 2026-03-31 -> 2026-05-29
2026-06-06 NCT04188405
Decitabine, Venetoclax, and Ponatinib for the Treatment of Philadelphia…
Trial completed
2026-06-06 NCT04188405
Decitabine, Venetoclax, and Ponatinib for the Treatment of Philadelphia…
date change Primary completion moved earlier: 2026-11-30 -> 2026-06-02
2026-06-06 NCT04188405
Decitabine, Venetoclax, and Ponatinib for the Treatment of Philadelphia…
date change Completion moved earlier: 2026-11-30 -> 2026-06-02
2026-06-04 NCT05091424
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a…
date change Primary completion pushed: 2028-05-31 -> 2031-02-10
2026-06-04 NCT05091424
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a…
date change Completion pushed: 2030-02-28 -> 2032-02-10
Showing 20 of 58 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-11 NCT07643103 Immuno-Targeted Therapy Plus Low-Dose Chemotherapy for Newly Diagnosed Adult Ph-Negative… Phase 2 Not Yet Recruiting
2026-06-09 NCT07635485 VA Induction and Bridging Transplantation for Hypoplastic/Secondary AML Not Yet Recruiting
2026-06-08 NCT07632170 The Efficacy and Safety of Selinisole Combined With Azacitidine and Venetoclax in the… Not Yet Recruiting
2026-06-04 NCT07626021 Selinexor Monotherapy for Cytoreduction in BCR::ABL1-Negative Myeloproliferative Neoplasms Phase 2 Not Yet Recruiting
2026-05-26 NCT07605949 Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML Phase 2 Not Yet Recruiting
2026-05-22 NCT07604233 Phase 1/2 FLAG-IDA, VEN and Asciminib in CML and Ph+ AML Phase 1/2 Not Yet Recruiting
Active Studies by Phase
Phase 4
1
Phase 3
33
Phase 2/3
9
Phase 2
106
Phase 1/2
48
Phase 1
57
Early Phase 1
2
Not specified
13
Active Trials — top 25 of 269
NCT IDTitleConditionStatus
Phase 4
NCT07044687 Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in… Acute Myeloid Leukemia Recruiting
Phase 3
NCT07132684 Comparison of VA and D/IA Induction Regimens in Elderly Fit Acute Myeloid Leukemia… AML, Adult Recruiting
NCT06428019 A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants… Chronic Lymphocytic Leukemia Recruiting
NCT05712694 Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With… Soft Tissue Sarcoma Recruiting
NCT05947851 A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line… Leukemia, Lymphocytic, Chronic, B-Cell Recruiting
NCT05183035 Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML) Acute Myeloid Leukemia Recruiting
NCT07138209 A Study Comparing QLS32015 Monotherapy Versus Pomalidomide, Dexamethasone (Pd) or… Relapsed or Refractory Multiple Myeloma Recruiting
NCT04628026 Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients… Acute Myeloid Leukemia Recruiting
NCT06846671 A Study of BGB-16673 Compared to Investigator's Choice in Participants With Chronic… CLL Recruiting
NCT07007312 Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With… Acute Myeloid Leukemia (AML) Recruiting
NCT07277231 A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With… Chronic Lymphocytic Leukemia Recruiting
NCT06943872 A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or… Chronic Lymphocytic Leukemia Recruiting
NCT06852222 A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With… Leukemia, Myeloid, Acute Recruiting
NCT06158841 Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard… Multiple Myeloma Recruiting
NCT04269902 Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or… Chronic Lymphocytic Leukemia Recruiting
NCT04965493 A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax… Chronic Lymphocytic Leukemia Active, Not Recruiting
NCT07407660 Shortened Venetoclax Duration Based on Day 14 BM Blasts Versus Standard Therapy in… Acute Myeloid Leukemia Not Yet Recruiting
NCT03336333 A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With… Chronic Lymphocytic Leukemia Active, Not Recruiting
NCT07478991 Azacytidine, Venetoclax Plus Minus Quizartinib for First Line Older/Unfit AML Patients… Acute Myeloid Leukemia, Adult Not Yet Recruiting
NCT07486479 Venetoclax, Azacitidine, and Mitoxantrone Hydrochloride Liposome Versus Idarubicin and… Acute Myeloid Leukemia (AML) Not Yet Recruiting
NCT04562389 Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis Myelofibrosis Active, Not Recruiting
NCT07469046 VAH vs VA in Newly Diagnosed Elderly AML Acute Myeloid Leukemia (AML) Not Yet Recruiting
NCT07539818 Azacitidine + Venetoclax VS Azacitidineas Maintenance Therapy in AML AML Not Yet Recruiting
NCT03768063 A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd… Cancer Active, Not Recruiting
NCT04608318 Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus… Chronic Lymphoid Leukemia Active, Not Recruiting
Sponsors Running Venetoclax Trials
Disease Areas
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