Clinical Trial

VA Induction and Bridging Transplantation for Hypoplastic/Secondary AML

Not Yet Recruiting
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Summary
The purpose of this study is to explore the efficacy and safety of venetoclax combined with azacitidine(VA) induction followed by bridging allogeneic hematopoietic stem cell transplantation (allo-HSCT) in the treatment of hypoplastic and secondary acute myeloid leukemia (AML).
Trial Details
NCT Number NCT07635485
Lead Sponsor The First Affiliated Hospital of Soochow University
Collaborators: Nanfang Hospital, Southern Medical University, Ruijin Hospital North Shanghai Jiao Tong University School of Medicine
Conditions Hypoplastic Acute Myeloid Leukemia, Secondary AML (Adult)
Enrollment 50 participants
Start Date 2026-06-01
Primary Completion 2029-05-31 (estimated)
Study Completion 2029-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-09