| Detected | Trial | Change |
|---|---|---|
| 2026-06-04 | NCT07277231 A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With… |
Trial sites expanded: 46 -> 66 locations |
| 2026-05-28 | NCT07277231 A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With… |
Trial sites expanded: 29 -> 46 locations |
| 2026-05-15 | NCT07341191 Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma… |
Recruitment opened |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-10 | NCT07638787 Pola-R-CHP Plus Sonrotoclax in Untreated BCL2-High/Double-Hit LBCL | Phase 1/2 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06742996 | A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared… | Mantle Cell Lymphoma | Recruiting |
| NCT07277231 | A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With… | Chronic Lymphocytic Leukemia | Recruiting |
| NCT06943872 | A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or… | Chronic Lymphocytic Leukemia | Recruiting |
| NCT07321652 | Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment… | Chronic Lymphocytic Leukemia | Not Yet Recruiting |
| NCT06073821 | Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax… | CLL | Active, Not Recruiting |
| Phase 2 | |||
| NCT06854003 | BRAZAN: A Randomized Phase 2 Study of Bendamustine, Rituximab, Cytarabine (AraC)… | Mantle Cell Lymphoma | Recruiting |
| NCT06839053 | Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic… | Chronic Lymphocytic Leukemia | Recruiting |
| NCT07341191 | Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma… | Mantle Cell Lymphoma | Recruiting |
| NCT06849713 | Zanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or… | Chronic Lymphocytic Leukemia | Recruiting |
| NCT07548710 | Study of SA+X in the Treatment of Newly Diagnosed AML | Acute Myeloid Leukemia | Recruiting |
| NCT05952037 | A Study to Investigate Efficacy and Safety of BCL2 Inhibitor Sonrotoclax as Monotherapy… | Waldenstrom Macroglobulinemia | Active, Not Recruiting |
| NCT07335887 | Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With… | AL Amyloidosis (AL) | Not Yet Recruiting |
| NCT05479994 | Study of BGB-11417 in Participants With Relapsed or Refractory Chronic Lymphocytic… | Leukemia | Active, Not Recruiting |
| NCT07508995 | A Phase 2 Trial Of The Bruton Tyrosine Kinase Degrader BGB-16673 In Combination With… | Chronic Lymphocytic Leukemia (CLL) | Not Yet Recruiting |
| NCT06497062 | Phase II Study of Sonrotoclax Combined With Chemotherapy in the Treatment of Newly… | Acute Myeloid Leukemia | Active, Not Recruiting |
| NCT07573670 | A Phase 2 Study of Bcl-2 Inhibitor Combined With Azacitidine for Newly Diagnosed Mixed… | Newly Diagnosed Mixed Phenotype Acute Leukemia | Not Yet Recruiting |
| NCT06637501 | A Study to Investigate Sonrotoclax Combined With Zanubrutinib Versus Zanubrutinib Alone… | Chronic Lymphocytic Leukemia | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT04771130 | A Study of BGB-11417 in Participants With Myeloid Malignancies | Acute Myeloid Leukemia | Recruiting |
| NCT04973605 | A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations… | Relapsed/Refractory Multiple Myeloma | Recruiting |
| NCT06634589 | A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other… | B-cell Malignancy | Recruiting |
| NCT06697184 | A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating… | Chronic Lymphocytic Leukemia | Recruiting |
| NCT07638787 | Pola-R-CHP Plus Sonrotoclax in Untreated BCL2-High/Double-Hit LBCL | Large B-cell Lymphoma | Not Yet Recruiting |
| Phase 1 | |||
| NCT06859008 | Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic… | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Recruiting |
| NCT04883957 | Study of BGB-11417 in Adult Participants With Mature B-cell Malignancies | Mature B-cell Malignancies | Active, Not Recruiting |
| NCT04277637 | Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell… | Mature B-Cell Malignancies | Active, Not Recruiting |