Drug Pipeline

Sodium bicarbonate Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12

Active Studies

Recruiting

Phase 3

Top Sponsors

Active Studies by Phase

Phase 4

Phase 3

Phase 2

Phase 1/2

Phase 1

Early Phase 1

Not specified

Active Trials

NCT ID	Title	Condition	Status
Phase 4
NCT05564130	Bicarbonate for In-Hospital Cardiac Arrest	Cardiac Arrest	Active, Not Recruiting
NCT07424625	A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac…	Metabolic Acidosis	Not Yet Recruiting
Phase 3
NCT05697770	SODium BICarbonate for Metabolic Acidosis in the ICU	Metabolic Acidosis	Active, Not Recruiting
Phase 2
NCT04984226	Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD	Chronic Kidney Diseases	Recruiting
Phase 1/2
NCT07408076	Sodium Bicarbonate as an Alternative to Potassium Citrate for Kidney Stones	Kidney Stones, Urolithiasis, Hypocitraturia	Not Yet Recruiting
Phase 1
NCT02411773	Sympatholysis in Chronic Kidney Disease	Chronic Kidney Disease	Recruiting
Early Phase 1
NCT04651088	Comparing Alkalinizing Agents Efficacy on Stone Risk in Patients on a Metabolically…	Kidney Stone	Not Yet Recruiting
Not specified
NCT07321379	Efficacy of Bicarbonate on the Risk of Assisted Delivery in Nulliparous Women With…	Prolonged Labor	Not Yet Recruiting
NCT05113641	Reducing Dietary Acid With Food Versus Oral Alkali in People With Chronic Kidney Disease…	Chronic Kidney Diseases	Active, Not Recruiting

Sponsors Running Sodium bicarbonate Trials

Emory University (1) University of Texas Southwestern Medical Center (1) University of California, Davis (1) Dylan MacKay (1) Lars Wiuff Andersen (1) Australian and New Zealand Intensive Care Research Centre (1) Copenhagen University Hospital, Hvidovre (1) University of California, Los Angeles (1) Mayo Clinic (1)

Disease Areas

Chronic Kidney Disease (3) Diabetes (1)

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