| Detected | Trial | Change |
|---|---|---|
| 2026-05-30 | NCT06115642 A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX43 in… |
overall status: "Recruiting" → "Enrolling By Invitation" |
| 2026-05-14 | NCT07113275 A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by… |
Recruitment opened |
| 2026-05-14 | NCT07113275 A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by… |
Primary endpoint(s) modified |
| 2026-05-14 | NCT07283692 Neoadjuvant Serplulimab Plus Weekly Paclitaxel and Carboplatin in TNBC (Neo-SERPENT) |
Recruitment opened |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-02 | NCT07621484 HIPEC Priming Followed by Serplulimab Plus SOX/XELOX in Locally Advanced Gastric Cancer | Phase 2 | Not Yet Recruiting |
| 2026-05-22 | NCT07604909 A Phase II Randomized Trial of Serplulimab With Second-Line Chemo/Targeted Therapy for… | Phase 2 | Recruiting |
| 2026-05-19 | NCT07596121 Serplulimab Monotherapy in Elderly Patients With NSCLC and PD-L1 TPS ≥ 50% | Phase 2 | Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT07446465 | FOLFOX Chemotherapy Combined With Fruquintinib and Serplulimab as First-Line Conversion… | Colorectal Cancer (Locally Advanced or Metastatic) | Not Yet Recruiting |
| Phase 3 | |||
| NCT07113275 | A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by… | Rectal Cancer | Recruiting |
| NCT05353257 | A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With… | Limited-Stage Small Cell Lung Cancer | Active, Not Recruiting |
| NCT07336953 | A Phase III, Randomized, Clinical Trial of GnP Combined With SBRT and Serplulimab Versus… | PDAC - Pancreatic Ductal Adenocarcinoma | Not Yet Recruiting |
| Phase 2/3 | |||
| NCT06280495 | Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT… | Colorectal Cancer | Recruiting |
| NCT07318883 | A Phase II/III Clinical Study to Evaluate HLX07 in Combination With Serplulimab and… | Squamous NSCLC | Not Yet Recruiting |
| Phase 2 | |||
| NCT06727617 | Serplulimab With Chemoradiotherapy for Postoperative Cervical Cancer With Risk Factors | Cervical Cancers | Recruiting |
| NCT07340489 | Serplulimab for Locally Advanced Cervical Cancer | Cervical Cancer | Recruiting |
| NCT05954429 | A Study to Explore the Third-line Treatment of Fruquintinib Combined With Serplulimab in… | Colorectal Cancer | Recruiting |
| NCT06461910 | Efficacy and Safety of Anti-PD-1, Thymalfasin, and SOX in Neoadjuvant Treatment of cStage… | Gastric Cancer | Recruiting |
| NCT05731726 | Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally… | pMMR | Recruiting |
| NCT07457528 | Efficacy and Safety of Neo-CRT Plus Serplulimab, Nimotuzumab in Patients With Locally… | Resectable Esophageal Squamous Cell Carcinoma | Recruiting |
| NCT06850103 | SCRT-CAPEOX-Serplulimab for MSS/pMMR Rectal Cancer With Oligometastases | Colorectal Carcinoma | Recruiting |
| NCT05957510 | Safety and Efficacy Evaluation of Serplulimab Plus Chemo in SCLC Transformed From… | Small-cell Lung Cancer | Recruiting |
| NCT07283692 | Neoadjuvant Serplulimab Plus Weekly Paclitaxel and Carboplatin in TNBC (Neo-SERPENT) | Triple Negative Breast Cancer | Recruiting |
| NCT07583511 | Teniposide, Cisplatin and Serplulimab for Treatment of ES-SCLC, a Randomized Controlled… | Small-cell Lung Cancer | Recruiting |
| NCT07596121 | Serplulimab Monotherapy in Elderly Patients With NSCLC and PD-L1 TPS ≥ 50% | NSCLC (Non-small Cell Lung Cancer) | Recruiting |
| NCT07604909 | A Phase II Randomized Trial of Serplulimab With Second-Line Chemo/Targeted Therapy for… | Colorectal Cancer | Recruiting |
| NCT07269782 | A Phase II Study to Evaluate the Efficacy and Safety of HLX43 + Serplulimab as… | Non Small Cell Lung Cancer | Recruiting |
| NCT06497530 | Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC | Extensive-Stage Small Cell Lung Cancer | Recruiting |
| NCT07381400 | Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally… | Rectal Cancer | Not Yet Recruiting |
| NCT07403435 | Short-course Radiotherapy Combined With Serplulimab and Chemotherapy as Neoadjuvant… | Esophageal Squamous Cell Carcinoma (ESCC) | Not Yet Recruiting |
| NCT07466303 | Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for… | Breast Cancer | Not Yet Recruiting |
| NCT07507916 | Dynamic ctDNA-Guided Adjuvant Therapy in cStage III and IVA Gastric or Gastroesophageal… | ctDNA | Not Yet Recruiting |
| NCT07527520 | Neoadjuvant Moderately Hypofractionated Radiotherapy Combined With Chemotherapy and… | Rectal Cancer | Not Yet Recruiting |