Drug Pipeline

Pevonedistat Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
5
Active Studies
0
Recruiting
4
Top Sponsors
Active Studies by Phase
Phase 2
2
Phase 1/2
2
Phase 1
1
Active Trials
NCT IDTitleConditionStatus
Phase 2
NCT03965689 Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in… Metastatic Lung Non-Small Cell Squamous Carcinoma Active, Not Recruiting
NCT04175912 Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the… Metastatic Cholangiocarcinoma Active, Not Recruiting
Phase 1/2
NCT03862157 Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute… Acute Myeloid Leukemia Active, Not Recruiting
NCT03330821 Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Active, Not Recruiting
Phase 1
NCT03479268 Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or… B-Cell Prolymphocytic Leukemia Active, Not Recruiting
Sponsors Running Pevonedistat Trials
National Cancer Institute (NCI) (2) University of Southern California (1) City of Hope Medical Center (1) M.D. Anderson Cancer Center (1)
Disease Areas
Leukemia (3) Acute Myeloid Leukemia (AML) (2) Myelodysplastic Syndromes (MDS) (2) Chronic Lymphocytic Leukemia (CLL) (1) Non-Hodgkin Lymphoma (1) DLBCL (1) Follicular Lymphoma (1) Mantle Cell Lymphoma (1) Chronic Myeloid Leukemia (CML) (1) Myelofibrosis (1)
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