| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT05777993 | A Study to Provide Continued Access to Mitapivat for Participants Who Previously… | Pyruvate Kinase Deficiency | Enrolling by Invitation |
| Phase 3 | |||
| NCT07506863 | A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in… | Transfusion-dependent Alpha-Thalassemia | Not Yet Recruiting |
| NCT07517133 | A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in… | Non-Transfusion-dependent Alpha-Thalassemia | Not Yet Recruiting |
| NCT04770753 | A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With… | Non-Transfusion-dependent Alpha-Thalassemia | Active, Not Recruiting |
| NCT04770779 | A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With… | Transfusion-dependent Alpha-Thalassemia | Active, Not Recruiting |
| NCT05144256 | A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With… | Pediatric Pyruvate Kinase Deficiency | Active, Not Recruiting |
| NCT05175105 | A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With… | Pediatric Pyruvate Kinase Deficiency | Active, Not Recruiting |
| Phase 2/3 | |||
| NCT05031780 | A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With… | Sickle Cell Disease | Active, Not Recruiting |
| Phase 2 | |||
| NCT03692052 | A Study to Determine the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of… | Thalassemia | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT04610866 | Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat… | Sickle Cell Disease | Active, Not Recruiting |