Drug Pipeline

FOLFIRI Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
15
Active Studies
10
Recruiting
3
Phase 3
10
Top Sponsors
2
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-29 NCT07221357
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy…
Trial sites expanded: 279 -> 286 locations
2026-05-27 NCT04929223
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of…
Trial sites expanded: 76 -> 82 locations
Active Studies by Phase
Phase 3
1
Phase 2/3
2
Phase 2
5
Phase 1/2
2
Phase 1
4
Early Phase 1
1
Active Trials
NCT IDTitleConditionStatus
Phase 3
NCT07389265 Continuation of Cetuximab Beyond First-Line Progression in Metastatic Colorectal Cancer Metastatic Colorectal Cancer (mCRC) Recruiting
Phase 2/3
NCT07221357 A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy… Untreated, Unresectable, or Metastatic Colorectal Cancer Recruiting
NCT03081143 Ramucirumab Plus FOLFIRI Versus Ramucirumab Plus Paclitaxel in Patients With Advanced or… Advanced Gastric or EGJ Cancer Active, Not Recruiting
Phase 2
NCT07061080 Refractory Advanced diGestive Neuroendocrine Carcinomas Treated With tARlatamab Advanced Neuroendocrine Carcinomas of The Digestive System Recruiting
NCT07011576 A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With… Colon Cancer Recruiting
NCT07446322 FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of… Ras-mutated Metastatic Colorectal Cancer Recruiting
NCT06106308 Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and… Metastatic Colorectal Cancer Active, Not Recruiting
NCT07337447 Trial of FOLFIRI + Zimberelimab + Domvanalimab vs FOLFIRI With a Hybrid Synthetic Control… Carcinoma, Neuroendocrine Not Yet Recruiting
Phase 1/2
NCT05786924 Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies Non-small Cell Lung Cancer Recruiting
NCT07391566 LPM6690176 in Combination With Chemotherapy and Bevacizumab in Metastatic Colorectal… Metastatic Colorectal Cancer (mCRC) Not Yet Recruiting
Phase 1
NCT04485013 TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers Cancer Recruiting
NCT06179160 A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors… Solid Tumors Recruiting
NCT06663319 A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers Colorectal Neoplasms Recruiting
NCT04929223 A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of… Metastatic Colorectal Cancer Recruiting
Early Phase 1
NCT07318389 ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic… Dynamic Tumor Resistance Not Yet Recruiting
Sponsors Running FOLFIRI Trials
Disease Areas
Get alerts when FOLFIRI trials change
Status changes, date slips, and new filings — detected daily, delivered to your inbox.
Start monitoring free