Drug Pipeline

Ex-Vivo expanded autologous IL-8 receptor (CXCR2) modified CD70 CAR (8R-70CAR) T cells Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
3
Active Studies
1
Recruiting
1
Top Sponsors
4
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-28 NCT05353530
IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma		 overall status: "Active Not Recruiting" → "Recruiting"
2026-05-23 NCT06946680
IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent…		 overall status: "Active Not Recruiting" → "Not Yet Recruiting"
2026-05-23 NCT06946680
IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent…		 Enrollment increased: 18 -> 24 participants
2026-05-23 NCT06946680
IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent…		 Trial arms changed: 1 -> 3
Active Studies by Phase
Phase 1
3
Active Trials
NCT IDTitleConditionStatus
Phase 1
NCT05353530 IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma Glioblastoma Multiforme Recruiting
NCT07569263 IL-8 Receptor Modified Patient-Derived Activated CD70 CAR T Cell Therapy in Adults With… Brain Metastases Not Yet Recruiting
NCT06946680 IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent… High-grade Glioma Not Yet Recruiting
Sponsors Running Ex-Vivo expanded autologous IL-8 receptor (CXCR2) modified CD70 CAR (8R-70CAR) T cells Trials
University of Florida (3)
Disease Areas
Glioblastoma (1) Glioma (1)
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