Drug Pipeline

Axatilimab Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
20
Active Studies
10
Recruiting
3
Phase 3
10
Top Sponsors
4
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-06 NCT05723055
Evaluating Combination of Nivolumab and Axatilimab in Patients With Relapsed/Refractory…
date change Primary completion pushed: 2026-05 -> 2026-12
2026-06-06 NCT05723055
Evaluating Combination of Nivolumab and Axatilimab in Patients With Relapsed/Refractory…
date change Completion pushed: 2028-04 -> 2028-11
2026-05-27 NCT06585774
A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic…
Trial sites expanded: 119 -> 122 locations
2026-05-23 NCT06388564
A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib…
overall status: "Recruiting" → "Active Not Recruiting"
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-10 NCT07638982 Axatilimab + CAR-T for High-Risk Lymphoma Phase 1 Not Yet Recruiting
Active Studies by Phase
Phase 3
3
Phase 2
10
Phase 1/2
4
Phase 1
3
Active Trials
NCT IDTitleConditionStatus
Phase 3
NCT06585774 A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic… Chronic Graft-versus-host-disease Recruiting
NCT06263478 A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Axatilimab Monotherapy… Chronic Graft-versus-host-disease Active, Not Recruiting
NCT06821542 A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic… Chronic Graft-versus-host-disease Active, Not Recruiting
Phase 2
NCT07011810 Axatilimab for Sclerotic Chronic Graft-versus-Host Disease Chronic Graft Versus Host Disease Recruiting
NCT05491226 Reinvigorating TNBC Response to Immunotherapy With Combination Myeloid Inhibition and… TNBC - Triple-Negative Breast Cancer Recruiting
NCT06663722 Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic… Chronic Graft Versus Host Disease Recruiting
NCT07124078 A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants… Chronic Graft-versus-host-disease Recruiting
NCT04710576 A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host… Chronic Graft-versus-host-disease Active, Not Recruiting
NCT06132256 MAXPIRe: Study to Evaluate Axatilimab in Participants With Idiopathic Pulmonary Fibrosis… Idiopathic Pulmonary Fibrosis Active, Not Recruiting
NCT07349771 Axatilimab Plus Standard of Care Therapy for the Prevention of Graft Versus Host Disease… Hematopoietic and Lymphatic System Neoplasm Not Yet Recruiting
NCT07015853 ASTRAEA: ReinvigorAting ReSponse To ImmunotheRApy in MEtAstatic TNBC With Combination… TNBC - Triple-Negative Breast Cancer Not Yet Recruiting
NCT06388564 A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib… Chronic Graft-versus-host-disease Active, Not Recruiting
NCT05723055 Evaluating Combination of Nivolumab and Axatilimab in Patients With Relapsed/Refractory… Hodgkin Lymphoma Active, Not Recruiting
Phase 1/2
NCT06320405 Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients… Advanced Malignant Solid Neoplasm Recruiting
NCT07128381 Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With… Myelofibrosis (MF) Recruiting
NCT06843408 A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or… Chronic Graft-versus-host-disease Recruiting
NCT06523556 Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase… Atypical Chronic Myeloid Leukemia Recruiting
Phase 1
NCT06959537 A Phase Ib Study of Novel Combination (New) of Low Dose Oral CyclophoSphamide (s) to… Breast Cancer Recruiting
NCT07511062 Axatilimab Combined With Decitabine/Venetoclax for the Treatment of TP53-mutated AML Acute Myeloid Leukemia Not Yet Recruiting
NCT07638982 Axatilimab + CAR-T for High-Risk Lymphoma Diffuse Large B Cell Lymphoma (DLBCL) Not Yet Recruiting
Sponsors Running Axatilimab Trials
Disease Areas
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