Disease landscape

Duchenne Muscular Dystrophy (DMD) clinical trials

Get alerts when Duchenne Muscular Dystrophy (DMD) trials change

50 active trials 24 recruiting 36 sponsors 4 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days

2026-08-12
critical
Primary completion pushed: 2029-11 → 2031-09
Completion pushed: 2029-11 → 2031-09
NCT05524883 Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in… · Dyne Therapeutics · Phase 1/2
2026-08-13
notable
Trial completed
NCT07347548 A Trial to Investigate the Safety and Pharmacokinetics of GRT6019 in Healthy Male… · Grünenthal GmbH · Phase 1
2026-08-20
minor
Trial sites expanded: 1 → 4 locations
NCT07092540 The Baby Duchenne Study: Characterizing Developmental and Clinical Outcomes in the First… · University of Rochester

Active trials by phase

Early Phase 1
5
Phase 1
4
Phase 1/2
4
Phase 2
7
Phase 2/3
1
Phase 3
3
Not charted: 26 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 50

NCT IDTitleSponsorStatusUpdated
Phase 3
NCT07608432 Efficacy, Safety, and Tolerability of Zeleciment Rostudirsen (DYNE-251) Administered… Dyne Therapeutics Recruiting 2026-05-27
NCT05881408 A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene… Sarepta Therapeutics, Inc. Active, Not Recruiting 2026-05-22
NCT03992430 A Study to Compare Safety and Efficacy of High Doses of Eteplirsen in Participants With… Sarepta Therapeutics, Inc. Active, Not Recruiting 2026-02-27
Phase 2/3
NCT05693142 AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy… REGENXBIO Inc. Active, Not Recruiting 2026-07-21
Phase 2
NCT05996003 NS-089/NCNP-02-201 in Boys With Duchenne Muscular Dystrophy (DMD) NS Pharma, Inc. Recruiting 2026-03-06
NCT06450639 A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy… Hoffmann-La Roche Active, Not Recruiting 2026-08-13
NCT06128564 A Gene Delivery Study to Evaluate the Safety and Expression of Delandistrogene… Hoffmann-La Roche Active, Not Recruiting 2026-08-10
NCT07573631 An Open-Label Extension Study to Evaluate the Long-term Safety and Efficacy of BMN 351 in… BioMarin Pharmaceutical Enrolling by Invitation 2026-07-24
NCT07682129 Long-Term Extension Study in Participants With Duchenne Muscular Dystrophy Amenable to… Entrada Therapeutics, Inc. Not Yet Recruiting 2026-07-02
NCT06867107 An Open-label Long-term Follow-up Study of SAT-3247 for Participants With Duchenne… Satellos Bioscience, Inc. Enrolling by Invitation 2026-04-23
NCT05135663 Extension Study of NS-089/NCNP-02 in DMD Nippon Shinyaku Co., Ltd. Active, Not Recruiting 2025-07-20
Phase 1/2
NCT07038824 A Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping to… Entrada Therapeutics, Inc. Recruiting 2026-08-13
NCT07037862 A Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 44 Skipping to… Entrada Therapeutics, Inc. Recruiting 2026-08-13
NCT05524883 Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in… Dyne Therapeutics Active, Not Recruiting 2026-08-11
NCT07642635 Glucagon-Like Peptide-1 Receptor Agonists to Attenuate Metabolic Risk in Individuals With… Vanderbilt University Medical Center Not Yet Recruiting 2026-06-11
Phase 1
NCT07172971 Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy Vanderbilt University Medical Center Recruiting 2026-08-24
NCT06817382 A Study to Investigate the Safety and Biodistribution of a Single Intrathecal (IT)… Insmed Gene Therapy LLC Recruiting 2026-07-28
NCT04626674 A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From… Sarepta Therapeutics, Inc. Recruiting 2026-06-24
NCT06114056 A Clinical Study Evaluating the Safety, Tolerability, and Initial Efficacy of Single… West China Hospital Active, Not Recruiting 2026-03-17
Early Phase 1
NCT07188012 Safety and Dystrophin Expression of SPOT-03 in Duchenne Muscular Dystrophy (DMD) Patients Shanghai Siponuoyin Biotechnology Co Ltd Recruiting 2026-05-07
NCT06900049 Evaluation of the Safety, Tolerability, and Efficacy of LE051 in Patients With Duchenne… Shanghai Jiao Tong University School of Medicine Recruiting 2025-04-02
NCT06641895 Evaluation of the Safety and Efficacy of BBM-D101 to Treat Patients with Duchenne… Shanghai Jiao Tong University School of Medicine Recruiting 2025-03-25
NCT07282652 A Study to Evaluate the Safety and Tolerability of RAG-18 in Pediatric Patients With… Peking Union Medical College Hospital Active, Not Recruiting 2026-01-16
NCT06392724 A Study to Evaluate the Safety and Tolerability of GEN6050X in Duchenne Muscular… Peking Union Medical College Hospital Active, Not Recruiting 2025-07-29
Not applicable
NCT07039799 The Effect of Virtual Reality Applications on Upper Extremity Functions in Patients With… Istanbul University Recruiting 2026-05-19

Top sponsors by active trials in this area

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