Sponsor pipeline

Dyne Therapeutics clinical trial pipeline

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Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

What changed in the last 30 days

1 trial changed in the last 30 days: 0 stopped, 0 with notable changes, 1 with a minor change only.

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.

Active trials by phase

Phase 1/2
2
Phase 3
2

Active trials

NCT IDTitleConditionStatusUpdated
Phase 3
NCT07486934 Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants… Myotonic Dystrophy Type 1 (DM1) Recruiting 2026-10-13
NCT07608432 Efficacy, Safety, and Tolerability of Zeleciment Rostudirsen (DYNE-251) Administered… Duchenne Muscular Dystrophy (DMD) Recruiting 2026-05-27
Phase 1/2
NCT05481879 Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in… Myotonic Dystrophy Type 1 (DM1) Active, Not Recruiting 2026-09-23
NCT05524883 Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in… Duchenne Muscular Dystrophy (DMD) Active, Not Recruiting 2026-08-11

Disease areas by active trials

Duchenne Muscular Dystrophy (2)

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